Recent Advances in Fluorescent Probes for Detection of HOCl and HNO

被引：68

作者：

Ashoka, Anila Hoskere ^{[2
]}

Ali, Firoj ^{[3
]}

Tiwari, Rajeshwari ^{[1
]}

Kumari, Rina ^{[1
]}

Pramanik, Sumit Kumar ^{[1
]}

Das, Amitava ^{[1
]}

机构：

[1] Cent Salt & Marine Chem Res Inst, CSIR, Bhavnagar, Gujarat, India

[2] Univ Strasbourg, Lab Bioimaging & Pathol, Strasbourg, France

[3] Cent Inst Min & Fuel Res, CSIR, Dhanbad, Bihar, India

来源：

ACS OMEGA | 2020年 / 5卷 / 04期

关键词：

HYPOCHLOROUS ACID; AQUEOUS-SOLUTION; NITROXYL HNO; OXYGEN; CHEMODOSIMETER; LYSOSOME; CANCER; ROS;

D O I：

10.1021/acsomega.9b03420

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

It is known that reactive oxygen (ROS) and nitrogen (RNS) species play a diverse role in various biological processes, such as inflammation, signal transduction, and neurodegenerative injury, apart from causing various diseases caused by oxidative and nitrosative stresses, respectively, by ROS and RNS. Thus, it is very important to quantify the concentration level of ROS and RNS in live cells, tissues, and organisms. Various small-molecule-based fluorescent/chemodosimetric probes are reported to quantify and map the effective distribution of ROS/RNS under in vitro/in vivo conditions with a great spatial and temporal resolution. Such reagents are now appreciated as an excellent tool for aiding breakthroughs in modern redox biology. This mini-review is a brief, but all-inclusive, account of such molecular probes that have been developed recently.

引用

页码：1730 / 1742

页数：13

共 49 条

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