Predictive value of lymphocyte-to-monocyte ratio in patients with contrast-induced nephropathy after percutaneous coronary intervention for acute coronary syndrome

被引：13

作者：

Karauzum, Irem ^{[1
]}

Karauzum, Kurtulus ^{[1
]}

Acar, Burak ^{[1
]}

Hanci, Kaan ^{[1
]}

Bildirici, Halil Ibrahim Ulas ^{[2
]}

Kilic, Teoman ^{[1
]}

Ural, Ertan ^{[1
]}

机构：

[1] Kocaeli Univ, Fac Med, Istanbul, Turkey

[2] Biruni Univ, Dept Cardiol, Istanbul, Turkey

来源：

JOURNAL OF TRANSLATIONAL INTERNAL MEDICINE | 2021年 / 9卷 / 02期

关键词：

lymphocyte-to-monocyte ratio; acute coronary syndrome; contrast-induced nephropathy; percutaneous coronary intervention; ACUTE KIDNEY INJURY; ELEVATION MYOCARDIAL-INFARCTION; TERM OUTCOMES; RISK-FACTORS; ASSOCIATION; NEUTROPHIL; PLATELET; DYSFUNCTION; UNDERWENT; SEVERITY;

D O I：

10.2478/jtim-2021-0024

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background and Objectives: Lymphocyte-to-monocyte ratio (LMR) has emerged as a new indirect marker of inflammation, which is associated with adverse outcomes in cardiovascular diseases. The aim of this study was to evaluate whether admission LMR is associated with contrast-induced nephropathy (CIN) in patients who underwent percutaneous coronary intervention for acute coronary syndrome (ACS). Methods: A total of 873 patients were assessed. LMR was calculated via dividing lymphocyte count by monocyte count. Results: LMR was significantly lower in the with-CIN group. ROC analysis showed that the LMR ratios <2.52 predicted CIN development with sensitivity of 66.3% and specificity of 55.8%. Multivariate analysis showed that eGFR, admission glucose, and LMR were independent predictors of CIN in patients with ACS. Conclusion: LMR is an easily accessible marker and could be used as a predictor of CIN in patients with ACS undergoing percutaneous coronary intervention.

引用

页码：123 / 130

页数：8

共 41 条

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