Cation Exchange Strategy for the Encapsulation of a Photoactive CO-Releasing Organometallic Molecule into Anionic Porous Frameworks

被引:29
作者
Carmona, Francisco J. [1 ]
Rojas, Sara [1 ]
Sanchez, Purification [1 ]
Jeremias, Helia [2 ]
Marques, Ana R. [3 ]
Romao, Carlos C. [2 ,3 ]
Choquesillo-Lazarte, Duane [4 ]
Navarro, Jorge A. R. [1 ]
Maldonado, Carmen R. [1 ]
Barea, Elisa [1 ]
机构
[1] Univ Granada, Dept Inorgan Chem, Av Fuentenueva S-N, Granada 18071, Spain
[2] Univ Nova Lisboa, Inst Tecnol Quim & Biol, EAN, Av Republ, P-2780157 Oeiras, Portugal
[3] Alfama Ltd, IBET, EAN, Av Republ, P-2780157 Oeiras, Portugal
[4] IACT CSIC, Lab Estudios Cristalog, Av Palmeras 4, Granada 18100, Spain
关键词
CARBON-MONOXIDE; MESOPOROUS SILICA; NANOPARTICLES; COMPLEXES; DELIVERY; RMS;
D O I
10.1021/acs.inorgchem.6b00674
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
The encapsulation of the photoactive, nontoxic, water-soluble, and air stable cationic CORM [Mn(tacn)(CO)(3)]Br (tacn = 1,4,7-triazacyclononane) in different inorganic porous matrixes, namely, the metalorganic framework bio-MOF-1, (NH2(CH3)(2))(2)[Zn-8(adeninate)(4)(BPDC)(6)]center dot 8DMF center dot 11H(2)O (BPDC = 4,4'-biphenyldicarboxylate), and the functionalized mesoporous silicas MCM-41-SO3H and SBA-15-SO3H, is achieved by a cation exchange strategy. The CO release from these loaded materials, under simulated physiological conditions, is triggered by visible light. The results show that the silica matrixes, which are unaltered under physiological conditions, slow the kinetics of CO release, allowing a more controlled CO supply. In contrast, bio-MOF-1 instability leads to the complete leaching of the CORM. Nevertheless, the degradation of the MOF matrix gives rise to an enhanced CO release rate, which is related to the presence of free adenine in the solution.
引用
收藏
页码:6525 / 6531
页数:7
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