Development and biological evaluation of cerium oxide loaded polycaprolactone dressing on cutaneous wound healing in nursing care

被引：20
作者：
Hao, Deying [2 ]
Zhang, Guanmei [3 ]
Gong, Yancui [4 ]
Ma, Zaimei [1 ]
机构：
[1] Third Peoples Hosp Linyi, Dept Emergency, Linyi 276023, Shandong, Peoples R China
[2] Linyi Cent Hosp, Dept Emergency, Linyi 276400, Shandong, Peoples R China
[3] Third Peoples Hosp Linyi, Dept Nursing, Linyi 276023, Shandong, Peoples R China
[4] Linyi Cent Hosp, Dept Orthopaed, Linyi 276400, Shandong, Peoples R China
来源：
MATERIALS LETTERS | 2020年 / 265卷 / 265期
关键词：
Cerium oxide; Biomaterials; Polymeric composites; Wound healing; Nursing care; CEO2; NANOPARTICLES; HYDROGEL; GREEN;
D O I：
10.1016/j.matlet.2020.127401
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
The increasing damage of cutaneous wound infection caused by harmful bacteria is an urgent challenge in nursing care. Herein, a new kind of skin wound dressing is reported by the incorporation of mesoporous CeO2 nanorods into the polycaprolactone (PCL) nanomembrane through an evaporation-induced self-assembly strategy. The nanocomposite membrane was investigated by scanning electron microscopy, X-ray diffraction analysis, and mechanical tensile testing. Also, the as-characterized robust PCL-CeO2 dressing shows high antimicrobial activity against Escherichia coli, and Staphylococcus aureus, strong wound healing effect, and satisfied biocompatibility. This study indicates that the PCL-CeO2 nanocomposite dressing has great potential for cutaneous wound healing application in nursing care. (C) 2020 Elsevier B.V. All rights reserved.
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页数：4
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