Targeted Gene Repair Facilitated by Peptide Nucleic Acids (PNA)

被引:26
|
作者
Nielsen, Peter E. [1 ,2 ]
机构
[1] Univ Copenhagen, Panum Inst, Fac Hlth Sci, Dept Cellular & Mol Med, DK-2200 Copenhagen N, Denmark
[2] Univ Copenhagen, Fac Pharmaceut Sci, Dept Med Chem, DK-2100 Copenhagen, Denmark
关键词
DNA recognition; nucleic acids; peptide nucleic acids; recombination; targeted gene repair; ZINC-FINGER NUCLEASES; INTERSTRAND CROSS-LINKS; DOUBLE-DUPLEX INVASION; DOUBLE-STRANDED DNA; GAMMA-PNAS; RECOMBINATION; SPECIFICITY; THALASSEMIA; MUTATION; THERAPY;
D O I
10.1002/cbic.201000346
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:2073 / 2076
页数:4
相关论文
共 50 条
  • [41] Flavin Conjugates for Delivery of Peptide Nucleic Acids
    Marlin, Fanny
    Simon, Philippe
    Bonneau, Stephanie
    Alberti, Patrizia
    Cordier, Celine
    Boix, Charlotte
    Perrouault, Loic
    Fossey, Aurelie
    Saison-Behmoaras, Tula
    Fontecave, Marc
    Giovannangeli, Carine
    CHEMBIOCHEM, 2012, 13 (17) : 2593 - 2598
  • [42] Nanotechnology for delivery of peptide nucleic acids (PNAs)
    Gupta, Anisha
    Bahal, Raman
    Gupta, Meera
    Glazer, Peter M.
    Saltzman, W. Mark
    JOURNAL OF CONTROLLED RELEASE, 2016, 240 : 302 - 311
  • [43] Efficient Gene Therapy of Pancreatic Cancer via a Peptide Nucleic Acid (PNA)-Loaded Layered Double Hydroxides (LDH) Nanoplatform
    Yu, Zhiguo
    Hu, Ping
    Xu, Yingying
    Bao, Qunqun
    Ni, Dalong
    Wei, Chenyang
    Shi, Jianlin
    SMALL, 2020, 16 (23)
  • [44] Multifunctional Delivery Systems for Peptide Nucleic Acids
    Volpi, Stefano
    Cancelli, Umberto
    Neri, Martina
    Corradini, Roberto
    PHARMACEUTICALS, 2021, 14 (01) : 1 - 31
  • [45] Peptide Nucleic Acid (PNA)-Guided Peptide Engineering of an Aptamer Sensor for Protease-Triggered Molecular Imaging
    Xiang, Zhichu
    Zhao, Jian
    Yi, Deyu
    Di, Zhenghan
    Li, Lele
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 60 (42) : 22659 - 22663
  • [46] Recognition of mismatched sites in double-stranded DNA by a pair of partially noncomplementary peptide nucleic acids
    Shibata, Masanari
    Shoji, Osami
    Aiba, Yuichiro
    CHEMISTRY LETTERS, 2024, 53 (12)
  • [47] Recognition of Target Site in Various Forms of DNA and RNA by Peptide Nucleic Acid (PNA): From Fundamentals to Practical Applications
    Liang, Xingguo
    Liu, Mengqin
    Komiyama, Makoto
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 2021, 94 (06) : 1737 - 1756
  • [48] Advantages of Peptide Nucleic Acids as Diagnostic Platforms for Detection of Nucleic Acids in Resource-Limited Settings
    Zhang, Ning
    Appella, Daniel H.
    JOURNAL OF INFECTIOUS DISEASES, 2010, 201 : S42 - S45
  • [49] Application strategies of peptide nucleic acids toward electrochemical nucleic acid sensors
    Lai, Qingteng
    Chen, Wei
    Zhang, Yanke
    Liu, Zhengchun
    ANALYST, 2021, 146 (19) : 5822 - 5835
  • [50] Blockade of plasmid replication mediated by peptide nucleic acids
    Michael R. Liebling
    Nainn-Tsyr Jou
    Wayne Fang
    James S. Louie
    Molecular Biotechnology, 2003, 25 : 229 - 240