Targeted Gene Repair Facilitated by Peptide Nucleic Acids (PNA)

被引：26
|
作者：
Nielsen, Peter E. [1 ,2 ]
机构：
[1] Univ Copenhagen, Panum Inst, Fac Hlth Sci, Dept Cellular & Mol Med, DK-2200 Copenhagen N, Denmark
[2] Univ Copenhagen, Fac Pharmaceut Sci, Dept Med Chem, DK-2100 Copenhagen, Denmark
来源：
CHEMBIOCHEM | 2010年 / 11卷 / 15期
关键词：
DNA recognition; nucleic acids; peptide nucleic acids; recombination; targeted gene repair; ZINC-FINGER NUCLEASES; INTERSTRAND CROSS-LINKS; DOUBLE-DUPLEX INVASION; DOUBLE-STRANDED DNA; GAMMA-PNAS; RECOMBINATION; SPECIFICITY; THALASSEMIA; MUTATION; THERAPY;
D O I：
10.1002/cbic.201000346
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：2073 / 2076
页数：4
相关论文
共 50 条
  • [31] Peptide nucleic acids (PNAs) containing thymine monomers derived from chiral amino acids: Hybridization and solubility properties of D-lysine PNA
    Haaima, G
    Lohse, A
    Buchardt, O
    Nielsen, PE
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1996, 35 (17) : 1939 - 1942
  • [32] Chemodosimeter for CuII detection based on cyclic peptide nucleic acids
    Kovacs, Janos
    Roedler, Thomas
    Mokhir, Andriy
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (46) : 7815 - 7817
  • [33] Precise Preparation of Supramolecular Spherical Nucleic Acids for Nucleolin-Targeted Gene Delivery
    Chen, Ming
    Miao, Siyuan
    Zhang, Yaqi
    Chang, Xueman
    Dai, Jun
    Chen, Chuxin
    Li, Shaoguang
    Li, Hui
    Xia, Fan
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2024, 63 (49)
  • [34] Native Chemical Ligation Directed by Photocleavable Peptide Nucleic Acid (PNA) Templates
    Middel, Stephen
    Panse, Cornelia H.
    Nawratil, Swantje
    Diederichsen, Ulf
    CHEMBIOCHEM, 2017, 18 (23) : 2328 - 2332
  • [35] Peptide-PNA conjugates: Targeted transport of antisense therapeutics into tumors
    Mier, W
    Eritja, R
    Mohammed, A
    Haberkorn, U
    Eisenhut, M
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2003, 42 (17) : 1968 - 1971
  • [36] Synthesis and Nucleic Acids Binding Properties of Diastereomeric Aminoethylprolyl Peptide Nucleic Acids (aepPNA)
    Ngamwiriyawong, Patcharee
    Vilaivan, Tirayut
    NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2011, 30 (02) : 97 - 112
  • [37] Targeting Cancer Gene Dependencies with Anthrax-Mediated Delivery of Peptide Nucleic Acids
    Lu, Zeyu
    Paolella, Brenton R.
    Truex, Nicholas L.
    Loftis, Alexander R.
    Liao, Xiaoli
    Rabideau, Amy E.
    Brown, Meredith
    Busanovich, John
    Beroukhim, Rameen
    Pentelute, Bradley L.
    ACS CHEMICAL BIOLOGY, 2020, 15 (06) : 1358 - 1369
  • [38] PEPTIDE NUCLEIC-ACIDS (PNAS) - POTENTIAL ANTISENSE AND ANTI-GENE AGENTS
    NIELSEN, PE
    EGHOLM, M
    BERG, RH
    BUCHARDT, O
    ANTI-CANCER DRUG DESIGN, 1993, 8 (01): : 53 - 63
  • [39] Recent advances in the field of peptide nucleic acids
    Howarth, Nicola M.
    LETTERS IN ORGANIC CHEMISTRY, 2006, 3 (07) : 495 - 503
  • [40] Hybridization studies with chiral peptide nucleic acids
    Lowe, G
    Vilaivan, T
    Westwell, MS
    BIOORGANIC CHEMISTRY, 1997, 25 (5-6) : 321 - 329
12345