Prevention of laboratory animal allergy

被引:42
作者
Fisher, R [1 ]
Saunders, WB [1 ]
Murray, SJ [1 ]
Stave, GM [1 ]
机构
[1] Glaxo Wellcome Inc, Res Triangle Pk, NC 27709 USA
关键词
D O I
10.1097/00043764-199807000-00005
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Laboratory animal allergy (LAA) is a significant occupational hazard for workers in a number of research settings, including the pharmaceutical industry. Prevention of allergy and asthma is important because the illness can affect health and career, In a major pharmaceutical company, in an effort to prevent LAA, a comprehensive program to reduce exposure to environmental allergens was developed. The program included education, engineering controls, administrative controls, use of personal protective equipment, and medical surveillance. A prospective survey of five years of data was completed to determine the effect of the program on the prevalence and incidence of LAA. After instituting this program, we found that the prevalence of LAA ranged from 12 %-22 % and that the incidence was reduced to zero during the last two years of observation, We conclude that LAA is preventable through the implementation of a comprehensive effort to reduce exposure to allergens.
引用
收藏
页码:609 / 613
页数:5
相关论文
共 25 条
[2]  
AOYAMA K, 1992, BRIT J IND MED, V49, P41
[3]  
BOTHAM PA, 1987, BIOLOGIST, V34, P162
[4]   ALLERGY TO LABORATORY-ANIMALS - A FOLLOW-UP-STUDY OF ITS INCIDENCE AND OF THE INFLUENCE OF ATOPY AND PREEXISTING SENSITIZATION ON ITS DEVELOPMENT [J].
BOTHAM, PA ;
LAMB, CT ;
TEASDALE, EL ;
BONNER, SM ;
TOMENSON, JA .
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 1995, 52 (02) :129-133
[5]   Allergy to laboratory animals among animal handlers [J].
Bryant, DH ;
Boscato, LM ;
Mboloi, PN ;
Stuart, MC .
MEDICAL JOURNAL OF AUSTRALIA, 1995, 163 (08) :415-418
[6]  
*DEP HLTH HUM SERV, 1995, VIT HLTH STAT CURR E
[8]  
Fuortes LJ, 1996, AM J IND MED, V29, P67, DOI 10.1002/(SICI)1097-0274(199601)29:1<67::AID-AJIM9>3.3.CO
[9]  
2-K
[10]   THE PREVALENCE OF ALLERGIC SKIN-TEST REACTIVITY TO 8 COMMON AEROALLERGENS IN THE UNITED-STATES POPULATION - RESULTS FROM THE 2ND NATIONAL-HEALTH AND NUTRITION EXAMINATION SURVEY [J].
GERGEN, PJ ;
TURKELTAUB, PC ;
KOVAR, MG .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1987, 80 (05) :669-679