Shape effect on non-covalent dimer stability using classic scaled particle theory

被引：7

作者：

Graziano, Giuseppe ^{[1
]}

机构：

[1] Univ Sannio, Dept Sci & Technol, Via Francesco Sanctis Snc, I-82100 Benevento, Italy

来源：

CHEMICAL PHYSICS LETTERS | 2020年 / 743卷

关键词：

CAVITY CREATION; WATER; DIMERIZATION; SOLVATION; ENERGY;

D O I：

10.1016/j.cplett.2020.137176

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The shape of two non-covalent dimers formed by different variants of the B1 domain of protein G plays an important role for their stability in water and aqueous solutions [Proc. Natl. Acad. Sci. U.S.A. 115 (2018) 10965]. I demonstrate how much the stabilization afforded by the decrease in solvent-excluded volume upon association depends on the shape of the dimers in water and aqueous sugar solutions, using classic scaled particle theory. There is a strong dependence upon the decrease in water accessible surface area associated with dimer formation, whose general significance deserves attention.

引用

页数：6

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