Biology of Germ Cell Tumors

被引：5
|
作者：
Ma, Yuk Ting [2 ]
Cullen, Michael H. [2 ]
Hussain, Syed A. [1 ,2 ]
机构：
[1] Univ Birmingham, Canc Res UK, Inst Canc Studies, Sch Canc Sci, Birmingham B15 2TT, W Midlands, England
[2] Univ Hosp Birmingham NHS Fdn Trust, Ctr Canc, Birmingham B15 2TH, W Midlands, England
来源：
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2011年 / 25卷 / 03期
关键词：
Testicular; Germ cell tumors; Biology; Cisplatin resistance; CARCINOMA-IN-SITU; COMPARATIVE GENOMIC HYBRIDIZATION; DNA MISMATCH REPAIR; ADENOSINE-TRIPHOSPHATASE ATP7B; CISPLATIN-INDUCED APOPTOSIS; HMG-DOMAIN PROTEIN; TESTICULAR CANCER; MICROSATELLITE INSTABILITY; CHEMOTHERAPEUTIC DRUGS; DIFFERENTIAL SENSITIVITIES;
D O I：
10.1016/j.hoc.2011.03.004
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Testicular cancer has been a model for a curable malignancy. The existence of an array of potential new therapies is the result of a prodigious effort in the researching and defining of the molecular components of the cancer phenotype and the subsequent rational design of agents to target candidate pathways. A better understanding of the molecular biology of cancer may also aid in guiding the most appropriate use of existing therapies, such as conventional chemotherapy.
引用
收藏
页码：457 / +
页数：16
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