Quantifying gait impairment in individuals affected by Charcot-Marie-Tooth disease: the usefulness of gait profile score and gait variable score

被引：8

作者：

Coghe, Giancarlo ^{[1
]}

Pau, Massimiliano ^{[2
]}

Mamusa, Elena ^{[3
]}

Pisano, Cinzia ^{[1
]}

Corona, Federica ^{[2
]}

Pilloni, Giuseppina ^{[2
]}

Porta, Micaela ^{[2
]}

Marrosu, Giovanni ^{[3
]}

Vannelli, Alessandro ^{[3
]}

Frau, Jessica ^{[1
]}

Lorefice, Lorena ^{[1
]}

Fenu, Giuseppe ^{[1
]}

Marrosu, Maria Giovanna ^{[1
]}

Cocco, Eleonora ^{[1
]}

机构：

[1] Univ Cagliari, Ctr Sclerosi Multipla, Dept Med Sci & Publ Hlth, Via Is Guadazzonis 2, I-09126 Cagliari, Italy

[2] Univ Cagliari, Dept Mech Chem & Mat Engn, Cagliari, Italy

[3] ATS Sardegna, Ctr Sclerosi Multipla, Cagliari, Italy

来源：

DISABILITY AND REHABILITATION | 2020年 / 42卷 / 05期

关键词：

Gait profile score; gait analysis; Charcot-Marie-Tooth disease; synthetic index; foot drop; CMT neuropathy score; CMT NEUROPATHY SCORE; CLINICAL-OUTCOME MEASURES; 2ND VERSION; RELIABILITY; CHILDREN; FAILURE;

D O I：

10.1080/09638288.2018.1506946

中图分类号：

R49 [康复医学];

学科分类号：

100215 ;

摘要：

Background: Gait analysis is a reliable tool to characterise ambulation in Charcot-Marie-Tooth, the obtained are complex data makes its use scarce in clinical practice. The use of synthetic measures may enable the clinician to easily interpret gait kinematics in Charcot-Marie-Tooth. Aims: To test the usefulness of Gait Profile Score as a method to quantify and monitor kinematic gait alterations in Charcot-Marie-Tooth. Methods: A group of patients with Charcot-Marie-Tooth and a control group underwent Gait Analysis. Neurological impairment was evaluated by means of the Charcot Marie Tooth neuropathy score in his original form and in the Rasch Analysis revised form. Differences in Kinematics scores induced by the pathology were assessed using the Mann-Whitney U test. The relationship between gait parameters and Charcot Marie Tooth neuropathy score was assessed by means of the Spearman correlation. Results: Twenty patients were enrolled. Mann-Whitney U test revealed a significant effect of the pathology on Gait Profile Score (p < 0.001). Charcot Marie Tooth neuropathy score was positively correlated with Gait Profile Score (Rho = 0.708, p = 0.001). Conclusion: Gait profile score can differentiate Charcot Marie Tooth from unaffected people and to quantify ambulation impairment, also identifying the joints more affected by the disease.

引用

页码：737 / 742

页数：6

共 21 条

[21] Gait patterns of children and adolescents with Charcot-Marie-Tooth disease [J].

Wojciechowski, Elizabeth ;

Sman, Amy ;

Cornett, Kayla ;

Raymond, Jacqueline ;

Refshauge, Kathryn ;

Menezes, Manoj P. ;

Burns, Joshua .

GAIT & POSTURE, 2017, 56 :89-94

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