State-of-the-art mandible reconstruction using revascularized free-tissue transfer

被引:17
作者
Emerick, Kevin S. [1 ]
Teknos, Theodoros N. [1 ]
机构
[1] Univ Michigan, Dept Otolaryngol, Ann Arbor, MI 48105 USA
关键词
bone graft; bone morphogenetic protein; distraction osteogeneis; free flap; mandible reconstruction; tissue engineering;
D O I
10.1586/14737140.7.12.1781
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Mandible defects are created by trauma as well as ablative surgery for both benign and malignant tumors. Ablative surgery for malignant tumors creates complex defects that impact form and function. This is often further complicated by the use of chemotherapy and radiation. In order to achieve a highly functional reconstruction with an acceptable cosmetic result, patients must be properly evaluated preoperatively. A patient's performance status and expectations for postoperative form and function can impact reconstruction. Once the defect is created, both the bone and soft-tissue loss must be considered. A structured approach to mandible defects will enable the re-establishment of mandible continuity and optimal soft-tissue reconstruction. This will ultimately lead to a patient with oral competence and limited swallowing deficits, as well as the ability to communicate effectively and interact with their community in a meaningful manner. There are ongoing investigations into new techniques and materials, such as distraction osteogenesis and tissue engineering, which will hopefully advance our ability to reconstruct the mandible.
引用
收藏
页码:1781 / 1788
页数:8
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