Oncostatin M promotes epithelial barrier dysfunction and is elevated in eosinophilic mucosal disease

被引：0
作者：
Pothoven, Kathryn [1 ]
Norton, James [1 ]
Suh, Lydia [1 ]
Carter, Roderick [1 ]
Hulse, Kathryn [1 ]
Liu, Mark [4 ,5 ,6 ]
Gonsalves, Nirmala [2 ]
Peters, Anju [1 ]
Harris, Kathleen [1 ]
Smith, Stephanie Shintani [3 ]
Conley, David [3 ]
Grammer, Leslie [1 ]
Kato, Atsushi [1 ]
Kern, Robert [3 ]
Bryce, Paul [1 ]
Tan, Bruce [3 ]
Schleimer, Robert [1 ,3 ]
机构：
[1] Northwestern Univ, Dept Med, Feinberg Sch Med, Div Allergy Immunol, Chicago, IL 60611 USA
[2] Northwestern Univ, Dept Med, Feinberg Sch Med, Div Gastroenterol & Hepatol, Chicago, IL 60611 USA
[3] Northwestern Univ, Dept Otolaryngol, Feinberg Sch Med, Chicago, IL 60611 USA
[4] Johns Hopkins Asthma & Allergy Ctr, Div Allergy & Clin Immunol, Baltimore, MD USA
[5] Johns Hopkins Asthma & Allergy Ctr, Div Pulm, Baltimore, MD USA
[6] Johns Hopkins Asthma & Allergy Ctr, Div Crit Care Med, Baltimore, MD USA
来源：
JOURNAL OF IMMUNOLOGY | 2015年 / 194卷
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
HYP7P.255
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Systemic imbalance in hormone levels associates with epithelial barrier dysfunction in allergic disease
    Berdnikovs, Sergejs
    Abdala-Valencia, Hiam
    Loffredo, Lucas F.
    Erickson, Kristin
    Browning, Mandy
    Saber, Rana
    Schleimer, Robert P.
    Singh, Anne Marie
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2017, 139 (02) : AB263 - AB263
  • [42] Genetic and Transcriptomic Bases of Intestinal Epithelial Barrier Dysfunction in Inflammatory Bowel Disease
    Vancamelbeke, Maaike
    Vanuytsel, Tim
    Farre, Ricard
    Verstockt, Sare
    Ferrante, Marc
    Van Assche, Gert
    Rutgeerts, Paul
    Schuit, Frans
    Vermeire, Severine
    Arijs, Ingrid
    Cleynen, Isabelle
    INFLAMMATORY BOWEL DISEASES, 2017, 23 (10) : 1718 - 1729
  • [43] CTRP3 promotes TNF-α-induced apoptosis and barrier dysfunction in salivary epithelial cells
    Mei, Mei
    Qu, Ling-Han
    Cong, Xin
    Zhang, Yan
    Xiang, Ruo-Lan
    Yu, Guang-Yan
    Su, Jia-Zeng
    Wu, Li-Ling
    CELLULAR SIGNALLING, 2021, 85
  • [44] Mend Your Fences The Epithelial Barrier and its Relationship With Mucosal Immunity in Inflammatory Bowel Disease
    Martini, Eva
    Krug, Susanne M.
    Siegmund, Britta
    Neurath, Markus F.
    Becker, Christoph
    CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2017, 4 (01): : 33 - 46
  • [45] NOX4 promotes mucosal barrier injury in inflammatory bowel disease by mediating macrophages M1 polarization through ROS
    Han, Chenyang
    Sheng, Yongjia
    Wang, Jin
    Zhou, Xiaohong
    Li, Wenyan
    Zhang, Caiqun
    Guo, Li
    Yang, Yi
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2022, 104
  • [46] Gut Mucosal Barrier Dysfunction, Microbial Dysbiosis, and Their Role in HIV-1 Disease Progression
    Mudd, Joseph C.
    Brenchley, Jason M.
    JOURNAL OF INFECTIOUS DISEASES, 2016, 214 : S58 - S66
  • [47] Berberine ameliorates intestinal mucosal barrier dysfunction in nonalcoholic fatty liver disease (NAFLD) rats
    Wang, Yuzhen
    Cui, Suxian
    Zheng, Jimin
    Li, Yueqin
    Li, Pingping
    Hou, Hongtao
    JOURNAL OF KING SAUD UNIVERSITY SCIENCE, 2020, 32 (05) : 2534 - 2539
  • [48] Restoring airway epithelial barrier dysfunction: a new therapeutic challenge in allergic airway disease
    Steelant, Brecht
    Seys, Sven F.
    Boeckxstaens, Guy
    Akdis, Cezmi A.
    Ceuppens, Jan L.
    Hellings, Peter W.
    RHINOLOGY, 2016, 54 (03) : 195 - 205
  • [49] microRNA-301a Induces Epithelial Barrier Dysfunction and Facilitates Intestinal Mucosal Inflammation and Colitis-Associated Cancer
    He, Chong
    Shi, Yan
    Sun, Mingming
    Yang, Wenjing
    Liu, Zhanju
    GASTROENTEROLOGY, 2016, 150 (04) : S60 - S60
  • [50] Intestinal epithelial barrier dysfunction induces IL-17 production by γδ intraepithelial lymphocytes: A novel mechanism of mucosal tolerance
    Edelblum, Karen L.
    Turner, Jerrold R.
    FASEB JOURNAL, 2012, 26
12345