Oncostatin M promotes epithelial barrier dysfunction and is elevated in eosinophilic mucosal disease

被引:0
|
作者
Pothoven, Kathryn [1 ]
Norton, James [1 ]
Suh, Lydia [1 ]
Carter, Roderick [1 ]
Hulse, Kathryn [1 ]
Liu, Mark [4 ,5 ,6 ]
Gonsalves, Nirmala [2 ]
Peters, Anju [1 ]
Harris, Kathleen [1 ]
Smith, Stephanie Shintani [3 ]
Conley, David [3 ]
Grammer, Leslie [1 ]
Kato, Atsushi [1 ]
Kern, Robert [3 ]
Bryce, Paul [1 ]
Tan, Bruce [3 ]
Schleimer, Robert [1 ,3 ]
机构
[1] Northwestern Univ, Dept Med, Feinberg Sch Med, Div Allergy Immunol, Chicago, IL 60611 USA
[2] Northwestern Univ, Dept Med, Feinberg Sch Med, Div Gastroenterol & Hepatol, Chicago, IL 60611 USA
[3] Northwestern Univ, Dept Otolaryngol, Feinberg Sch Med, Chicago, IL 60611 USA
[4] Johns Hopkins Asthma & Allergy Ctr, Div Allergy & Clin Immunol, Baltimore, MD USA
[5] Johns Hopkins Asthma & Allergy Ctr, Div Pulm, Baltimore, MD USA
[6] Johns Hopkins Asthma & Allergy Ctr, Div Crit Care Med, Baltimore, MD USA
来源
JOURNAL OF IMMUNOLOGY | 2015年 / 194卷
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
HYP7P.255
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Oncostatin M promotes mucosal epithelial barrier dysfunction, and its expression is increased in patients with eosinophilic mucosal disease
    Pothoven, Kathryn L.
    Norton, James E.
    Hulse, Kathryn E.
    Suh, Lydia A.
    Carter, Roderick G.
    Rocci, Erin
    Harris, Kathleen E.
    Shintani-Smith, Stephanie
    Conley, David B.
    Chandra, Rakesh K.
    Liu, Mark C.
    Kato, Atsushi
    Gonsalves, Nirmala
    Grammer, Leslie C., III
    Peters, Anju T.
    Kern, Robert C.
    Bryce, Paul J.
    Tan, Bruce K.
    Schleimer, Robert P.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2015, 136 (03) : 737 - +
  • [2] Oncostatin M Is Elevated in Mucosal Disease and May Mediate Epithelial Barrier Dysfunction in Vivo
    Pothoven, Kathryn L.
    Norton, James E.
    Suh, Lydia
    Carter, Roderick G.
    Hulse, Kathryn E.
    Rocci, Erin
    Gonsalves, Nirmala
    Liu, Mark C.
    Peters, Anju T.
    Harris, Kathleen E.
    Smith, Stephanie Shintani
    Conley, David B.
    Grammer, Leslie C.
    Kato, Atsushi
    Kern, Robert C.
    Bryce, Paul
    Tan, Bruce
    Schleimer, Robert P.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2015, 135 (02) : AB80 - AB80
  • [3] Oncostatin M is produced by neutrophils, and promotes epithelial barrier dysfunction in mucosal airways disease
    Pothoven, Kathryn L.
    Norton, James E.
    Suh, Lydia A.
    Carter, Roderick G.
    Welch, Kevin C.
    Shintani-Smith, Stephanie
    Conley, David B.
    Grammer, Leslie
    Peters, Anju T.
    Liu, Mark C.
    Kato, Atsushi
    Kern, Robert C.
    Tan, Bruce K.
    Schleimer, Robert P.
    JOURNAL OF IMMUNOLOGY, 2016, 196
  • [4] Oncostatin M promotes epithelial barrier dysfunction in patients with eosinophilic chronic rhinosinusitis with nasal polyps
    Wang, Bao-Feng
    Wang, Ying-Ying
    Lin, Hai
    Yi, Yun-Lan
    TISSUE BARRIERS, 2024,
  • [5] Neutrophils are a major source of the epithelial barrier disrupting cytokine oncostatin M in patients with mucosal airways disease
    Pothoven, Kathryn L.
    Norton, James E.
    Suh, Lydia A.
    Carter, Roderick G.
    Harris, Kathleen E.
    Biyasheva, Assel
    Welch, Kevin
    Shintani-Smith, Stephanie
    Conley, David B.
    Liu, Mark C.
    Kato, Atsushi
    Avila, Pedro C.
    Hamid, Qutayba
    Grammer, Leslie C., III
    Peters, Anju T.
    Kern, Robert C.
    Tan, Bruce K.
    Schleimer, Robert P.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2017, 139 (06) : 1966 - +
  • [6] Elevated Intestinal Interleukin-13 Promotes Intestinal Epithelial Barrier Dysfunction
    Wu, D. X.
    Ahrens, R. E.
    Groschwitz, K. R.
    Osterfield, H. N.
    Foster, P. S.
    Finkelman, F. D.
    Matthaei, K. I.
    Hogan, S. P.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2009, 123 (02) : S186 - S186
  • [7] Chlorination of epithelial tight junction proteins by neutrophil myeloperoxidase promotes barrier dysfunction and mucosal inflammation
    Cartwright, Ian M.
    Zhou, Liheng
    Koch, Samuel D.
    Welch, Nichole
    Zakharov, Daniel
    Callahan, Rosemary
    Steiner, Calen A.
    Gerich, Mark E.
    Onyiah, Joseph C.
    Colgan, Sean P.
    JCI INSIGHT, 2024, 9 (14)
  • [8] Detergent exposure induces epithelial barrier dysfunction and eosinophilic inflammation in the esophagus
    Doyle, Alfred D.
    Masuda, Mia Y.
    Pyon, Grace C.
    Luo, Huijun
    Putikova, Arina
    LeSuer, William E.
    Flashner, Samuel
    Rank, Matthew A.
    Nakagawa, Hiroshi
    Kita, Hirohito
    Wright, Benjamin L.
    ALLERGY, 2023, 78 (01) : 192 - 201
  • [9] Oncostatin M Is Elevated In Chronic Rhinosinusitis and Decreases Barrier Function In Human Airway Epithelium
    Pothoven, Kathryn L.
    Norton, James
    Ocampo, Christopher
    Suh, Lydia
    Carter, Roderick
    Hulse, Kathryn E.
    Seshadri, Sudarshan
    Tan, Bruce K.
    Chandra, Rakesh
    Peters, Anju T.
    Harris, Kathleen E.
    Conley, David
    Grammer, Leslie C.
    Kern, Robert C.
    Schleimer, Robert P.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 133 (02) : AB237 - AB237
  • [10] Oncostatin M Contributes to Airway Epithelial Cell Dysfunction in Chronic Rhinosinusitis with Nasal Polyps
    Carsuzaa, Florent
    Bequignon, Emilie
    Bartier, Sophie
    Coste, Andre
    Dufour, Xavier
    Bainaud, Matthieu
    Lecron, Jean Claude
    Louis, Bruno
    Tringali, Stephane
    Favot, Laure
    Fieux, Maxime
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (07)