Zoonotic pathogens in fluctuating common vole (Microtus arvalis) populations: occurrence and dynamics

被引:24
作者
Rodriguez-Pastor, Ruth [1 ,2 ]
Escudero, Raquel [3 ]
Lambin, Xavier [4 ]
Dolors Vidal, Ma [5 ]
Gil, Horacio [3 ]
Jado, Isabel [3 ]
Rodriguez-Vargas, Manuela [3 ]
Jose Luque-Larena, Juan [1 ,2 ]
Mougeot, Francois [6 ]
机构
[1] Univ Valladolid, Dept Ciencias Agroforestales, ETSIIAA, Avda Madrid 44, Palencia 34004, Spain
[2] Inst Univ Invest Gest Forestal Sostenible, Palencia, Spain
[3] Inst Salud Carlos III, Lab Referenda & Invest Patogenos Especiales, Ctr Natl Microbiol, Madrid 28220, Spain
[4] Univ Aberdeen, Sch Biol Sci, Aberdeen, Scotland
[5] Univ Castilla La Mancha, Fac Med, Area Microbiol, E-13071 Ciudad Real, Spain
[6] CSIC UCLM JCCM, IREC, Inst Invest Recursos Cineget, Ronda de Toledo S-N, Ciudad Real 13071, Spain
关键词
Bartonella; fleas; Francisella tularensis; rodent; and arthropod-borne pathogens; Microtus arvalis; mixed infections; population outbreaks; zoonotic diseases dynamics; BARTONELLA SPP; SMALL MAMMALS; FRANCISELLA-TULARENSIS; MOLECULAR METHOD; INFECTION; NORTHERN; RODENTS; FLEAS; FIELD; WILD;
D O I
10.1017/S0031182018001543
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Diseases and host dynamics are linked, but their associations may vary in strength, be time-lagged, and depend on environmental influences. Where a vector is involved in disease transmission, its dynamics are an additional influence, and we often lack a general understanding on how diseases, hosts and vectors interact. We report on the occurrence of six zoonotic arthropod-borne pathogens (Anaplasma, Bartonella, Borrelia, Coxiella, Francisella and Rickettsia) in common voles (Microtus arvalis) throughout a population fluctuation and how their prevalence varies according to host density, seasonality and vector prevalence. We detected Francisella tularensis and four species of Bartonella, but not Anaplasma, Borrelia, Coxiella or Rickettsia. Bartonella taylorii and B. grahamii prevalence increased and decreased with current host (vole and mice) density, respectively, and increased with flea prevalence. Bartonella doshiae prevalence decreased with mice density. These three Bartonella species were also more prevalent during winter. Bartonella rochalimae prevalence varied with current and previous vole density (delayed-density dependence), but not with season. Coinfection with F. tularensis and Bartonella occurred as expected from the respective prevalence of each disease in voles. Our results highlight that simultaneously considering pathogen, vector and host dynamics provide a better understanding of the epidemiological dynamics of zoonoses in farmland rodents.
引用
收藏
页码:389 / 398
页数:10
相关论文
共 51 条
[1]  
Anda P, 2012, Patent No. [EP1895015B1, 1895015]
[2]  
[Anonymous], 2017, R LANG ENV STAT COMP
[3]  
[Anonymous], 2006, BASIC EPIDEMIOLOGY
[4]  
[Anonymous], 2015, J CROHNS COLITIS S1, V9, pS15
[5]   Tularemia induces different biochemical responses in BALB/c mice and common voles [J].
Bandouchova, Hana ;
Sedlackova, Jana ;
Pohanka, Miroslav ;
Novotny, Ladislav ;
Hubalek, Martin ;
Treml, Frantisek ;
Vitula, Frantisek ;
Pikula, Jiri .
BMC INFECTIOUS DISEASES, 2009, 9
[6]   Tick-borne zoonotic bacteria in wild and domestic small mammals in northern Spain [J].
Barandika, J. F. ;
Hurtado, A. ;
Garcia-Esteban, C. ;
Gil, H. ;
Escudero, R. ;
Barral, M. ;
Jado, I. ;
Juste, R. A. ;
Anda, P. ;
Garcia-Perez, A. L. .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2007, 73 (19) :6166-6171
[7]   CONTEMPORARY VIEWS ON INTERRELATIONSHIPS BETWEEN FLEAS AND PATHOGENS OF HUMAN AND ANIMAL DISEASES [J].
BIBIKOVA, VA .
ANNUAL REVIEW OF ENTOMOLOGY, 1977, 22 :23-32
[8]   Bartonellae as elegant hemotropic parasites [J].
Birtles, RJ .
RICKETTSIOSES: FROM GENOME TO PROTEOME, PATHOBIOLOGY, AND RICKETTSIAE AS AN INTERNATIONAL THREAT, 2005, 1063 :270-279
[9]   Co-infection of Borrelia afzelii and Bartonella spp. in bank voles from a suburban forest [J].
Buffet, Jean-Philippe ;
Marsot, Maud ;
Vaumourin, Elise ;
Gasqui, Patrick ;
Masseglia, Sebastien ;
Marcheteau, Elie ;
Huet, Dominique ;
Chapuis, Jean-Louis ;
Pisanu, Benoit ;
Ferquel, Elisabeth ;
Halos, Lenaig ;
Vourc'h, Gwenael ;
Vayssier-Taussat, Muriel .
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES, 2012, 35 (06) :583-589
[10]   Drivers of Bartonella infection in micromammals and their fleas in a Mediterranean peri-urban area [J].
Cevidanes, Aitor ;
Altet, Laura ;
Chirife, Andrea D. ;
Proboste, Tatiana ;
Millan, Javier .
VETERINARY MICROBIOLOGY, 2017, 203 :181-188