Long-term immunologic response in HIV-infected patients with CD4 cell counts ≤50/mm3 when initiating protease inhibitor therapy.
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作者:
Le Moing, V
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机构:Hop Bichat Claude Bernard, Serv Malad Infect & Trop, F-75877 Paris 18, France
Le Moing, V
Eid, Z
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机构:Hop Bichat Claude Bernard, Serv Malad Infect & Trop, F-75877 Paris 18, France
Eid, Z
Ecobichon, JL
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机构:Hop Bichat Claude Bernard, Serv Malad Infect & Trop, F-75877 Paris 18, France
Ecobichon, JL
Duval, X
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机构:Hop Bichat Claude Bernard, Serv Malad Infect & Trop, F-75877 Paris 18, France
Duval, X
Longuet, P
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机构:Hop Bichat Claude Bernard, Serv Malad Infect & Trop, F-75877 Paris 18, France
Longuet, P
Elbim, C
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机构:Hop Bichat Claude Bernard, Serv Malad Infect & Trop, F-75877 Paris 18, France
Elbim, C
Brun-Vezinet, F
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机构:Hop Bichat Claude Bernard, Serv Malad Infect & Trop, F-75877 Paris 18, France
Brun-Vezinet, F
Leport, C
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机构:Hop Bichat Claude Bernard, Serv Malad Infect & Trop, F-75877 Paris 18, France
Leport, C
Vilde, JL
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机构:Hop Bichat Claude Bernard, Serv Malad Infect & Trop, F-75877 Paris 18, France
Vilde, JL
机构:
[1] Hop Bichat Claude Bernard, Serv Malad Infect & Trop, F-75877 Paris 18, France
[2] Hop Bichat Claude Bernard, Serv Immunohematol, F-75877 Paris, France
[3] Hop Bichat Claude Bernard, Serv Virol, F-75877 Paris 18, France
来源:
ANNALES DE MEDECINE INTERNE
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2001年
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152卷
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01期
关键词:
HIV infection;
AIDS;
protease inhibitors;
D O I:
暂无
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
From March to July 1996, 61 patients with CD4 < 50/mm(3) began a therapy with protease inhibitors. Increase and maintenance of CD4 > 100/mm(3) was observed in 39/61 patients with a protective effect for occurrence of AIDS or death. This immunological response was correlated with the duration of the virological response. However, 38% of patients with long-term immunological response never had a undetectable viral Load.