The importance of uromodulin as regulator of salt reabsorption along the thick ascending limb

被引：15
作者：
Zacchia, Miriam [1 ]
Capasso, Giovambattista [1 ]
机构：
[1] Univ Naples 2, Dept Cardiovasc Med, Naples, Italy
来源：
NEPHROLOGY DIALYSIS TRANSPLANTATION | 2015年 / 30卷 / 02期
关键词：
TAMM-HORSFALL PROTEIN; DAMAGE;
D O I：
10.1093/ndt/gfu365
中图分类号：
R3 [基础医学]; R4 [临床医学];
学科分类号：
1001 ; 1002 ; 100602 ;
摘要：
[No abstract available]
引用
收藏
页码：158 / 160
页数：3
相关论文
共 14 条
[1]   Renal effects of Tamm-Horsfall protein (uromodulin) deticiency in mice [J].
Bachmann, S ;
Mutig, K ;
Bates, J ;
Welker, P ;
Geist, B ;
Gross, V ;
Luft, FC ;
Alenina, N ;
Bader, M ;
Thiele, BJ ;
Prasadan, K ;
Raffi, HS ;
Kumar, S .
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2005, 288 (03) :F559-F567
[2]   A transgenic mouse model for uromodulin-associated kidney diseases shows specific tubulo-interstitial damage, urinary concentrating defect and renal failure [J].
Bernascone, Ilenia ;
Janas, Sylvie ;
Ikehata, Masami ;
Trudu, Matteo ;
Corbelli, Alessandro ;
Schaeffer, Celine ;
Rastaldi, Maria Pia ;
Devuyst, Olivier ;
Rampoldi, Luca .
HUMAN MOLECULAR GENETICS, 2010, 19 (15) :2998-3010
[3]   Tamm-Horsfall protein or uromodulin: new ideas about an old molecule [J].
Devuyst, O ;
Dahan, K ;
Pirson, Y .
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2005, 20 (07) :1290-1294
[4]   Paradoxical response to furosemide in uromodulin-associated kidney disease [J].
Labriola, Laura ;
Olinger, Eric ;
Belge, Hendrica ;
Pirson, Yves ;
Dahan, Karin ;
Devuyst, Olivier .
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2015, 30 (02) :330-335
[5]   Activation of the Bumetanide-sensitive Na+, K+,2Cl- Cotransporter (NKCC2) Is Facilitated by Tamm-Horsfall Protein in a Chloride-sensitive Manner [J].
Mutig, Kerim ;
Kahl, Thomas ;
Saritas, Turgay ;
Godes, Michael ;
Persson, Pontus ;
Bates, James ;
Raffi, Hajamohideen ;
Rampoldi, Luca ;
Uchida, Shinichi ;
Hille, Carsten ;
Dosche, Carsten ;
Kumar, Satish ;
Castaneda-Bueno, Maria ;
Gamba, Gerardo ;
Bachmann, Sebastian .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (34) :30200-30210
[6]   The Pharmacological Characteristics of Molecular-Based Inherited Salt-Losing Tubulopathies [J].
Nozu, Kandai ;
Iijima, Kazumoto ;
Kanda, Kyoko ;
Nakanishi, Koichi ;
Yoshikawa, Norishige ;
Satomura, Kenichi ;
Kaito, Hiroshi ;
Hashimura, Yuya ;
Ninchoji, Takeshi ;
Komatsu, Hiroshi ;
Kamei, Koichi ;
Miyashita, Ritsuko ;
Kugo, Masaaki ;
Ohashi, Hiroshi ;
Yamazaki, Hajime ;
Mabe, Hiroyo ;
Otsubo, Asa ;
Igarashi, Takashi ;
Matsuo, Masafumi .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2010, 95 (12) :E511-E518
[7]   The rediscovery of uromodulin (Tamm-Horsfall protein): from tubulointerstitial nephropathy to chronic kidney disease [J].
Rampoldi, Luca ;
Scolari, Francesco ;
Amoroso, Antonio ;
Ghiggeri, GianMarco ;
Devuyst, Olivier .
KIDNEY INTERNATIONAL, 2011, 80 (04) :338-347
[8]   Tamm-Horsfall Glycoprotein Interacts with Renal Outer Medullary Potassium Channel ROMK2 and Regulates Its Function [J].
Renigunta, Aparna ;
Renigunta, Vijay ;
Saritas, Turgay ;
Decher, Niels ;
Mutig, Kerim ;
Waldegger, Siegfried .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (03) :2224-2235
[9]   The Physiology of Urinary Concentration: An Update [J].
Sands, Jeff M. ;
Layton, Harold E. .
SEMINARS IN NEPHROLOGY, 2009, 29 (03) :178-195
[10]   Urinary secretion and extracellular aggregation of mutant uromodulin isoforms [J].
Schaeffer, Celine ;
Cattaneo, Angela ;
Trudu, Matteo ;
Santambrogio, Sara ;
Bernascone, Ilenia ;
Giachino, Daniela ;
Caridi, Gianluca ;
Campo, Andrea ;
Murtas, Corrado ;
Benoni, Simona ;
Izzi, Claudia ;
De Marchi, Mario ;
Amoroso, Antonio ;
Ghiggeri, Gian Marco ;
Scolari, Francesco ;
Bachi, Angela ;
Rampoldi, Luca .
KIDNEY INTERNATIONAL, 2012, 81 (08) :769-778
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