Polysaccharide Monoxygenases: Giving a Boost to Biofuel Production

被引：1

作者：

Wilmot, Carrie M. ^{[1
]}

机构：

[1] Univ Minnesota, Dept Biochem Mol Biol & Biophys, Minneapolis, MN 55455 USA

来源：

STRUCTURE | 2012年 / 20卷 / 06期

关键词：

GLYCOSIDE HYDROLASE FAMILY;

D O I：

10.1016/j.str.2012.05.006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this issue of Structure, Li et al. present high resolution crystal structures of two fungal polysaccharide monoxygenases. Unexpectedly, they observe oxygen species bound at the active sites that inform on the chemistry that can be supported by these enzymes. Additionally, the organization of aromatic amino acids and glycosylation on the carbohydrate binding surfaces suggests that regiospecificity and cellulose orientation can be predicted.

引用

页码：938 / 940

页数：3

共 13 条

[1] Biomass pretreatment: Fundamentals toward application [J].

Agbor, Valery B. ;

Cicek, Nazim ;

Sparling, Richard ;

Berlin, Alex ;

Levin, David B. .

BIOTECHNOLOGY ADVANCES, 2011, 29 (06) :675-685

[2] Oxidative Cleavage of Cellulose by Fungal Copper-Dependent Polysaccharide Monooxygenases [J].

Beeson, William T. ;

Phillips, Christopher M. ;

Cate, Jamie H. D. ;

Marletta, Michael A. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (02) :890-892

[3] Extracellular Aldonolactonase from Myceliophthora thermophila [J].

Beeson, William T. ;

Iavarone, Anthony T. ;

Hausmann, Corinne D. ;

Cate, Jamie H. D. ;

Marletta, Michael A. .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2011, 77 (02) :650-656

[4] Carbohydrate-binding modules: fine-tuning polysaccharide recognition [J].

Boraston, AB ;

Bolam, DN ;

Gilbert, HJ ;

Davies, GJ .

BIOCHEMICAL JOURNAL, 2004, 382 (03) :769-781

[5]

Chandel A. K., 2011, CRIT REV BIOTECHNOL, V1, DOI [DOI 10.3109/07388551.2011.595385, 10.3109/07388551.2011.595385]

[6] Cryocooling and radiation damage in macromolecular crystallography [J].

Garman, EF ;

Owen, RL .

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2006, 62 :32-47

[7] Stimulation of Lignocellulosic Biomass Hydrolysis by Proteins of Glycoside Hydrolase Family 61: Structure and Function of a Large, Enigmatic Family [J].

Harris, Paul V. ;

Welner, Ditte ;

McFarland, K. C. ;

Re, Edward ;

Poulsen, Jens-Christian Navarro ;

Brown, Kimberly ;

Salbo, Rune ;

Ding, Hanshu ;

Vlasenko, Elena ;

Merino, Sandy ;

Xu, Feng ;

Cherry, Joel ;

Larsen, Sine ;

Lo Leggio, Leila .

BIOCHEMISTRY, 2010, 49 (15) :3305-3316

[8] The First Structure of a Glycoside Hydrolase Family 61 Member, Cel61B from Hypocrea jecorina, at 1.6 Å Resolution [J].

Karkehabadi, Saeid ;

Hansson, Henrik ;

Kim, Steve ;

Piens, Kathleen ;

Mitchinson, Colin ;

Sandgren, Mats .

JOURNAL OF MOLECULAR BIOLOGY, 2008, 383 (01) :144-154

[9] Structural Basis for Substrate Targeting and Catalysis by Fungal Polysaccharide Monooxygenases [J].

Li, Xin ;

Beeson, William T. ;

Phillips, Christopher M. ;

Marletta, Michael A. ;

Cate, Jamie H. D. .

STRUCTURE, 2012, 20 (06) :1051-1061

[10] Cellobiose Dehydrogenase and a Copper-Dependent Polysaccharide Monooxygenase Potentiate Cellulose Degradation by Neurospora crassa [J].

Phillips, Christopher M. ;

Beeson, William T. ;

Cate, Jamie H. ;

Marletta, Michael A. .

ACS CHEMICAL BIOLOGY, 2011, 6 (12) :1399-1406

← 1 2 →