Acute on Chronic Liver Failure: Definition and Implications

被引：3
作者：
Aday, Ariel [1 ]
O'Leary, Jacqueline G. [1 ,2 ]
机构：
[1] Univ Texas Southwestern, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
[2] Dallas Vet Affairs Med Ctr, 4500 South Lancaster Rd, Dallas, TX 75216 USA
来源：
CLINICS IN LIVER DISEASE | 2020年 / 24卷 / 03期
关键词：
Acute on chronic liver failure; Cirrhosis; Dysbiosis; Organ failure; Liver transplant; ACUTE KIDNEY INJURY; BETA-BLOCKERS; BACTERIAL-INFECTIONS; CONSENSUS RECOMMENDATIONS; PACIFIC ASSOCIATION; CIRRHOSIS; MORTALITY; MANAGEMENT; SURVIVAL; GUT;
D O I：
10.1016/j.cld.2020.04.004
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Acute on chronic liver failure (ACLF) is an inflammation-based disorder that occurs in patients with underlying liver disease and is characterized by hepatic and extrahepatic organ failure. Morbidity and mortality are high in patients with ACLF, and therefore prevention and early identification are critical to improve outcome. The purpose of this article is to define ACLF, describe ways to identify the expected outcome of ACLF after development, and illustrate interventions to prevent it and when it is not preventable reduce associated morbidity and mortality.
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页码：521 / +
页数：15
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