Sensitive detection of Penicillin-G chemical using SnO2•YbO nanomaterials by electrochemical approach

In this approach, binary tin oxide doped ytterbium oxide nanosheets (SnO2 center dot YbO NSs) were synthesized in an alkaline phase using under low-temperature facile hydrothermal technique. Traditional methods such as UV-Visible spectroscopy, Fourier Transform Infra-Red Spectroscopy (FTIR), Powder X-ray diffraction (XRD), Field Emission Scanning Microscopy (FESEM) equipped with X-ray electron dispersive spectroscopy (XEDS), and X-ray photoelectron spectroscopy (XPS) were used to fully characterize the prepared SnO2 center dot YbO NSs. Fabrication of a thin-coating with doped NSs onto GCE by using 5% nafion conducting binder resulted in development of a selective and enzyme-free penicillin-G sensor probe. A reliable I-V technique was used to perform electrochemical performances of good sensitivity, large LDR, and long-term stability of the desired Penicillin-G sensor (SnO2 center dot YbO NSs/GCE/Nf). With a wide range of Penicillin-G concentration, the proposed calibration plot is noticed good linearity (R-2 = 0.9830). Sensitivity and LOD of the sensor were calculated as 24.75 mu A mu M-l cm(-2) and 30.0 pM, respectively based on S/N = 3 formula. Real samples (Human and rabbit serum, milk, and red-sea water) were analyzed with the fabricated SnO2 center dot YbO NSs/GCE/Nf sensor probe and the findings results were acceptable and satisfactory. This approach could be a noble development of in-situ Penicillin-G sensor based on binary SnO2 center dot YbO NSs/GCE/Nf by reliable I-V technique for important sensing applications including beneficial doped nanomaterials and nano-technological system. (C) 2021 The Author(s). Published by Elsevier B.V. on behalf of King Saud University.