Synthesis and characterization of silver nanoparticles using Caesalpinia pulcherrima flower extract and assessment of their in vitro antimicrobial, antioxidant, cytotoxic, and genotoxic activities

被引：73

作者：

Moteriya, Pooja ^{[1
]}

Chanda, Sumitra ^{[1
]}

机构：

[1] Saurashtra Univ, Dept Biosci UGC CAS, Rajkot 360005, Gujarat, India

来源：

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY | 2017年 / 45卷 / 08期

关键词：

Silver nanoparticles; characterization; antimicrobial activity; antioxidant activity; cytotoxicity; genotoxicity; GREEN SYNTHESIS; DNA-DAMAGE; BIOLOGICAL-ACTIVITIES; LEAF EXTRACT; ANTIBACTERIAL; BIOSYNTHESIS; MECHANISM; APOPTOSIS; LATEX; CELLS;

D O I：

10.1080/21691401.2016.1261871

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Caesalpinia pulcherrima flower extract mediated synthesis of silver nanoparticles was attempted in the present work including optimization of some procedure parameters. Characterization of synthesized silver nanoparticles was done by various spectral analyses. The size of synthesized silver nanoparticles was 12nm and they were spherical in shape. The green synthesized silver nanoparticles were further evaluated for antimicrobial, antioxidant, cytotoxic, and genotoxic activities; they showed good antimicrobial, antioxidant, and cytotoxic effects. Genotoxic study revealed non-toxic nature at lower concentration. Overall results suggest that the synthesized silver nanoparticles have pronounced applicability in pharmaceutical and biomedical field.

引用

页码：1556 / 1567

页数：12

共 54 条

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