Medicinal treatment of retroperitoneal soft tissue sarcomas

被引：0

作者：

Falkenhorst, Johanna ^{[1
]}

Hamacher, Rainer ^{[1
]}

Bauer, Sebastian ^{[1
]}

机构：

[1] Univ Duisburg Essen, Univ Klinikum Essen, Sarkomzentrum amWestdeutschen Tumorzentrum, Hufelandstr 55, D-45147 Essen, Germany

来源：

CHIRURG | 2022年 / 93卷 / 01期

关键词：

Chemotherapy; Sarcoma; Leiomyosarcoma; Liposarcoma; Evidence; ADJUVANT CHEMOTHERAPY; OPEN-LABEL; PROGNOSTIC-FACTORS; EWINGS-SARCOMA; MULTICENTER; SURVIVAL; OSTEOSARCOMA; EXTREMITIES; IFOSFAMIDE; THERAPY;

D O I：

10.1007/s00104-021-01539-x

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Retroperitoneal soft tissue sarcomas represent extreme challenges for interdisciplinary treatment teams. The sarcoma-specific experience of surgeons has the greatest impact on the survival of patients; however, too many patients still die despite optimal local treatment. The role of chemotherapy is undisputed only for patients with highly malignant bone sarcomas or rhabdomyosarcomas. For soft tissue sarcomas in adult patients, especially liposarcomas and leiomyosarcomas, the evidence situation is very unsatisfactory. This overview article discusses the complex data situation and controversial aspects that are relevant for current treatment decisions in interdisciplinary treatment teams.

引用

页码：40 / 47

页数：8

共 32 条

[21] Survival Outcomes Associated With 3 Years vs 1 Year of Adjuvant Imatinib for Patients With High-Risk Gastrointestinal Stromal Tumors An Analysis of a Randomized Clinical Trial After 10-Year Follow-up [J].

Joensuu, Heikki ;

Eriksson, Mikael ;

Hall, Kirsten Sundby ;

Reichardt, Annette ;

Hermes, Barbara ;

Schuette, Jochen ;

Cameron, Silke ;

Hohenberger, Peter ;

Jost, Philipp J. ;

Al-Batran, Salah-Eddin ;

Lindner, Lars H. ;

Bauer, Sebastian ;

Wardelmann, Eva ;

Nilsson, Bengt ;

Kallio, Raija ;

Jaakkola, Panu ;

Junnila, Jouni ;

Alvegard, Thor ;

Reichardt, Peter .

JAMA ONCOLOGY, 2020, 6 (08) :1241-1246

[22] MULTIMODAL THERAPY FOR THE MANAGEMENT OF PRIMARY, NONMETASTATIC EWINGS-SARCOMA OF BONE - A LONG-TERM FOLLOW-UP OF THE 1ST INTERGROUP STUDY [J].

NESBIT, ME ;

GEHAN, EA ;

BURGERT, EO ;

VIETTI, TJ ;

CANGIR, A ;

TEFFT, M ;

EVANS, R ;

THOMAS, P ;

ASKIN, FB ;

KISSANE, JM ;

PRITCHARD, DJ ;

HERRMANN, J ;

NEFF, J ;

MAKLEY, JT ;

GILULA, L .

JOURNAL OF CLINICAL ONCOLOGY, 1990, 8 (10) :1664-1674

[23] Response to anti-PD1 therapy with nivolumab in metastatic sarcomas [J].

Paoluzzi, L. ;

Cacavio, A. ;

Ghesani, M. ;

Karambelkar, A. ;

Rapkiewicz, A. ;

Weber, J. ;

Rosen, G. .

CLINICAL SARCOMA RESEARCH, 2016, 6

[24] The impact of chemotherapy on survival of patients with extremity and trunk wall soft tissue sarcoma: revisiting the results of the EORTC-STBSG 62931 randomised trial [J].

Pasquali, Sandro ;

Pizzamiglio, Sara ;

Touati, Nathan ;

Litiere, Saskia ;

Marreaud, Sandrine ;

Kasper, Bernd ;

Gelderblom, Hans ;

Stacchiotti, Silvia ;

Judson, Ian ;

Dei Tos, Angelo P. ;

Verderio, Paolo ;

Casali, Paolo G. ;

Woll, Penella J. ;

Gronchi, Alessandro .

EUROPEAN JOURNAL OF CANCER, 2019, 109 :51-60

[25] High-risk soft tissue sarcomas treated with perioperative chemotherapy: Improving prognostic classification in a randomised clinical trial [J].

Pasquali, Sandro ;

Colombo, Chiara ;

Pizzamiglio, Sara ;

Verderio, Paolo ;

Callegaro, Dario ;

Stacchiotti, Silvia ;

Broto, Javier Martin ;

Lopez-Pousa, Antonio ;

Ferrari, Stefano ;

Poveda, Andres ;

De Paoli, Antonino ;

Quagliuolo, Vittorio ;

Cruz Jurado, Josefina ;

Comandone, Alessandro ;

Grignani, Giovanni ;

De Sanctis, Rita ;

Palassini, Elena ;

Llomboart-Bosch, Antonio ;

Dei Tos, Angelo Paolo ;

Casali, Paolo G. ;

Picci, Piero ;

Gronchi, Alessandro .

EUROPEAN JOURNAL OF CANCER, 2018, 93 :28-36

[26] Results of the EICESS-92 study:: Two randomized trials of Ewing's sarcoma treatment -: Cyclophosphamide compared with ifosfamide in standard-risk patients and assessment of benefit of etoposide added to standard treatment in high-risk patients [J].

Paulussen, Michael ;

Craft, Alan W. ;

Lewis, Ian ;

Hackshaw, Allan ;

Douglas, Carolyn ;

Dunst, Juergen ;

Schuck, Andreas ;

Winkelmann, Winfried ;

Koehler, Gabriele ;

Poremba, Christopher ;

Zoubek, Andreas ;

Ladenstein, Ruth ;

van den Berg, Henk ;

Hunold, Andrea ;

Cassoni, Anna ;

Spooner, David ;

Grimer, Robert ;

Whelan, Jeremy ;

McTiernan, Anne ;

Juergens, Herbert .

JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (27) :4385-4393

[27] A systematic meta-analysis of randomized controlled trials of adjuvant chemotherapy for localized resectable soft-tissue sarcoma [J].

Pervaiz, Nabeel ;

Colterjohn, Nigel ;

Farrokhyar, Forough ;

Tozer, Richard ;

Figueredo, Alvaro ;

Ghert, Michelle .

CANCER, 2008, 113 (03) :573-581

[28] Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial [J].

Tawbi, Hussein A. ;

Burgess, Melissa ;

Bolejack, Vanessa ;

Van Tine, Brian A. ;

Schuetze, Scott M. ;

Hu, James ;

D'Angelo, Sandra ;

Attia, Steven ;

Riedel, Richard F. ;

Priebat, Dennis A. ;

Movva, Sujana ;

Davis, Lara E. ;

Okuno, Scott H. ;

Reed, Damon R. ;

Crowley, John ;

Butterfield, Lisa H. ;

Salazar, Ruth ;

Rodriguez-Canales, Jaime ;

Lazar, Alexander J. ;

Wistuba, Ignacio I. ;

Baker, Laurence H. ;

Maki, Robert G. ;

Reinke, Denise ;

Patel, Shreyaskumar .

LANCET ONCOLOGY, 2017, 18 (11) :1493-1501

[29] Retroperitoneal sarcomas: patterns of care in advanced stages, prognostic factors and focus on main histological subtypes: a multicenter analysis of the French Sarcoma Group [J].

Toulmonde, M. ;

Bonvalot, S. ;

Ray-Coquard, I. ;

Stoeckle, E. ;

Riou, O. ;

Isambert, N. ;

Bompas, E. ;

Penel, N. ;

Delcambre-Lair, C. ;

Saada, E. ;

Lecesne, A. ;

Le Pechoux, C. ;

Blay, J. Y. ;

Piperno-Neumann, S. ;

Chevreau, C. ;

Bay, J. O. ;

Brouste, V. ;

Terrier, P. ;

Ranchere-Vince, D. ;

Neuville, A. ;

Italiano, A. .

ANNALS OF ONCOLOGY, 2014, 25 (03) :730-734

[30] Mature tertiary lymphoid structures predict immune checkpoint inhibitor efficacy in solid tumors independently of PD-L1 expression [J].

Vanhersecke, Lucile ;

Brunet, Maxime ;

Guegan, Jean-Philippe ;

Rey, Christophe ;

Bougouin, Antoine ;

Cousin, Sophie ;

Le Moulec, Sylvestre ;

Besse, Benjamin ;

Loriot, Yohann ;

Larroquette, Mathieu ;

Soubeyran, Isabelle ;

Toulmonde, Maud ;

Roubaud, Guilhem ;

Pernot, Simon ;

Cabart, Mathilde ;

Chomy, Francois ;

Lefevre, Corentin ;

Bourcier, Kevin ;

Kind, Michele ;

Giglioli, Ilenia ;

Sautes-Fridman, Catherine ;

Velasco, Valerie ;

Courgeon, Felicie ;

Oflazoglu, Ezoglin ;

Savina, Ariel ;

Marabelle, Aurelien ;

Soria, Jean-Charles ;

Bellera, Carine ;

Sofeu, Casimir ;

Bessede, Alban ;

Fridman, Wolf H. ;

Le Loarer, Francois ;

Italiano, Antoine .

NATURE CANCER, 2021, 2 (08) :794-+

← 1 2 3 4 →