Segmentation of positron emission tomography images: Some recommendations for target delineation in radiation oncology

被引:131
作者
Lee, John A. [1 ]
机构
[1] Catholic Univ Louvain, Ctr Mol Imaging & Expt Radiotherapy IMRE 5469, B-1200 Brussels, Belgium
关键词
Radiation oncology; Positron emission tomography; Image segmentation; Target delineation; Uptake threshold; Validation methodology; GROSS TUMOR VOLUME; CELL LUNG-CANCER; STANDARDIZED UPTAKE VALUE; PET IMAGES; FDG-PET; ITERATIVE DECONVOLUTION; THRESHOLD SEGMENTATION; RADIOTHERAPY TARGET; GUIDED IMRT; HEAD;
D O I
10.1016/j.radonc.2010.07.003
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Positron emission tomography can be used in radiation oncology for the delineation of target volumes in the treatment planning stage. Numerous publications deal with this topic and the scientific community has investigated many methodologies, ranging from simple uptake thresholding to very elaborate probabilistic models. Nevertheless, no consensus seems to emerge. This paper reviews delineation techniques that are popular in the literature. Special attention is paid to threshold-based techniques and the caveats of this methodology are pointed out by formal analysis. Next, a simple model of positron emission tomography is suggested in order to shed some light on the difficulties of target delineation and how they might be eventually overcome. Validation aspects are considered as well. Finally, a few recommendations are gathered in the conclusion. (C) 2010 European Society for Therapeutic Radiology and Oncology and European Association of Nuclear Medicine. Published by Elsevier Ireland Ltd. All rights reserved. 96 (2010) 302-307
引用
收藏
页码:302 / 307
页数:6
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