All-optical highly sensitive akinetic sensor for ultrasound detection and photoacoustic imaging

被引:96
作者
Preisser, Stefan [1 ,2 ]
Rohringer, Wolfgang [1 ,2 ]
Liu, Mengyang [2 ]
Kollmann, Christian [2 ]
Zotter, Stefan [1 ]
Fischer, Balthasar [1 ]
Drexler, Wolfgang [2 ]
机构
[1] XARION Laser Acoust GmbH, Ghegastr 3, A-1030 Vienna, Austria
[2] Med Univ Vienna, Ctr Med Phys & Biomed Engn, Wahringer Gurtel 18-20,AKH 4L, A-1090 Vienna, Austria
来源
BIOMEDICAL OPTICS EXPRESS | 2016年 / 7卷 / 10期
关键词
MICROSCOPY; TOMOGRAPHY; SPEED;
D O I
10.1364/BOE.7.004171
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A novel all-optical akinetic ultrasound sensor, consisting of a rigid, fiber-coupled Fabry-Perot etalon with a transparent central opening is presented. The sensing principle relies exclusively on the detection of pressure-induced changes of the refractive index in the fluid filling the Fabry-Perot cavity. This enables resonance-free, inherently linear signal detection over a broad bandwidth. We demonstrate that the sensor achieves a exceptionally low peak noise equivalent pressure (NEP) values of 2 Pa over a 20MHz measurement bandwidth (without signal averaging), while maintaining a flat frequency response, and a detection bandwidth up to 22.5MHz (-6 dB). The measured large full field of view of the sensor is 2.7mm x 1.3mm and the dynamic range is 137 dB/root Hz or 63 dB at 20MHz bandwidth. For different required amplitude ranges the upper amplitude detection limit can be customized from at least 2 kPa to 2MPa by using cavity mirrors with a lower optical reflectivity. Imaging tests on a resolution target and on biological tissue show the excellent suitability of the akinetic sensor for optical resolution photoacoustic microscopy (OR-PAM) applications. (C) 2016 Optical Society of America
引用
收藏
页码:4171 / 4186
页数:16
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