The role of actin bundling proteins in the assembly of filopodia in epithelial cells

被引：50
作者：
Khurana, Seema [1 ]
George, Sudeep P. [1 ]
机构：
[1] Univ Houston, Dept Biol & Biochem, Houston, TX 77030 USA
来源：
CELL ADHESION & MIGRATION | 2011年 / 5卷 / 05期
关键词：
epithelial cell; fascin; villin; actin bundling; PIP2; binding; collective cell migration; microvilli; EMT; metastases; INSULIN-RECEPTOR SUBSTRATE; DROSOPHILA DORSAL CLOSURE; MICROVILLAR CORE PROTEINS; INTESTINAL BRUSH-BORDERS; VILLIN-LIKE PROTEIN; IN-VIVO; ALPHA-ACTININ; ELEGANS HYPODERMIS; JUNCTION FORMATION; DENDRITIC NETWORK;
D O I：
10.4161/cam.5.5.17644
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The goal of this review is to highlight how emerging new models of filopodia assembly which include tissue specific actin-bundling proteins could provide more comprehensive representations of filopodia assembly that would describe more adequately and effectively the complexity and plasticity of epithelial cells. This review also describes how the true diversity of actin bundling proteins must be considered to predict the far-reaching significance and versatile functions of filopodia in epithelial cells.
引用
收藏
页码：409 / 420
页数：12
相关论文
共 198 条
  • [11] Mechanical constraint imposed on plasma membrane through transverse phospholipid imbalance induces reversible actin polymerization via phosphoinositide 3-kinase activation
    Bettache, N
    Baisamy, L
    Baghdiguian, S
    Payrastre, B
    Mangeat, P
    Bienvenüe, A
    [J]. JOURNAL OF CELL SCIENCE, 2003, 116 (11) : 2277 - 2284
  • [12] Two distinct modes of guidance signalling during collective migration of border cells
    Bianco, Ambra
    Poukkula, Minna
    Cliffe, Adam
    Mathieu, Juliette
    Luque, Carlos M.
    Fulga, Tudor A.
    Rorth, Pernille
    [J]. NATURE, 2007, 448 (7151) : 362 - U12
  • [13] ProSAP/Shank postsynaptic density proteins interact with insulin receptor tyrosine kinase substrate IRSp53
    Bockmann, J
    Kreutz, MR
    Gundelfinger, ED
    Böckers, TM
    [J]. JOURNAL OF NEUROCHEMISTRY, 2002, 83 (04) : 1013 - 1017
  • [14] Actin machinery: pushing the envelope
    Borisy, GG
    Svitkina, TM
    [J]. CURRENT OPINION IN CELL BIOLOGY, 2000, 12 (01) : 104 - 112
  • [15] FIMBRIN, A NEW MICROFILAMENT-ASSOCIATED PROTEIN PRESENT IN MICROVILLI AND OTHER CELL-SURFACE STRUCTURES
    BRETSCHER, A
    WEBER, K
    [J]. JOURNAL OF CELL BIOLOGY, 1980, 86 (01) : 335 - 340
  • [16] Myosin IIB is required for growth cone motility
    Bridgman, PC
    Dave, S
    Asnes, CF
    Tullio, AN
    Adelstein, RS
    [J]. JOURNAL OF NEUROSCIENCE, 2001, 21 (16) : 6159 - 6169
  • [17] Bronner-Fraser Marianne, 1993, Trends in Cell Biology, V3, P392, DOI 10.1016/0962-8924(93)90089-J
  • [18] Molecular Model of the Microvillar Cytoskeleton and Organization of the Brush Border
    Brown, Jeffrey W.
    McKnight, C. James
    [J]. PLOS ONE, 2010, 5 (02):
  • [19] Bacterial Guanine Nucleotide Exchange Factors SopE-Like and WxxxE Effectors
    Bulgin, Richard
    Raymond, Benoit
    Garnett, James A.
    Frankel, Gad
    Crepin, Valerie F.
    Berger, Cedric N.
    Arbeloa, Ana
    [J]. INFECTION AND IMMUNITY, 2010, 78 (04) : 1417 - 1425
  • [20] EspT triggers formation of lamellipodia and membrane ruffles through activation of Rac-1 and Cdc42
    Bulgin, Richard R.
    Arbeloa, Ana
    Chung, Jade C. S.
    Frankel, Gad
    [J]. CELLULAR MICROBIOLOGY, 2009, 11 (02) : 217 - 229
12345678910