First Report of a Verona Integron-Encoded Metallo-β-Lactamase-Producing Klebsiella pneumoniae Infection in a Child in the United States

被引：5

作者：

Tamma, Pranita D. ^{[1
]}

Suwantarat, Nuntra ^{[2
,3
]}

Rudin, Susan D. ^{[4
]}

Logan, Latania K. ^{[6
,7
]}

Simner, Patricia J. ^{[2
]}

Rojas, Laura J. ^{[4
,8
,9
]}

Mojica, Maria F. ^{[4
,8
,10
]}

Carroll, Karen C. ^{[2
]}

Bonomo, Robert A. ^{[5
,8
,9
,10
,11
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Div Pediat Infect Dis, Baltimore, MD USA

[2] Johns Hopkins Univ, Sch Med, Dept Med Microbiol, Baltimore, MD USA

[3] Thammasat Univ, Chulabhorn Int Coll Med, Pathum Thani, Thailand

[4] Louis Stokes Cleveland Dept Vet Affairs Med Ctr, Res Serv, Cleveland, OH USA

[5] Louis Stokes Cleveland Dept Vet Affairs Med Ctr, Geriatr Res Educ & Clin Ctr, Cleveland, OH USA

[6] Rush Univ, Rush Med Coll, Med Ctr, Sect Pediat Infect Dis,Dept Pediat, Chicago, IL 60612 USA

[7] Case Western Reserve Univ, Sch Med, Louis Stokes Cleveland Dept Vet Affairs Med Ctr, Cleveland, OH USA

[8] Case Western Reserve Univ, Sch Med, Dept Med, Cleveland, OH 44106 USA

[9] Case Western Reserve Univ, Sch Med, Dept Mol Biol & Microbiol, Cleveland, OH USA

[10] Case Western Reserve Univ, Sch Med, Dept Biochem, Cleveland, OH 44106 USA

[11] Case Western Reserve Univ, Sch Med, Dept Pharmacol, Cleveland, OH 44106 USA

来源：

JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY | 2016年 / 5卷 / 03期

基金：

美国国家卫生研究院;

关键词：

carbapenemase; CRE; metallo-beta-lactamase; pediatrics; VIM; GRAM-NEGATIVE PATHOGENS; INTENSIVE-CARE-UNIT; RESISTANT ENTEROBACTERIACEAE; GENE; BLA(VIM-7); ISOLATE;

D O I：

10.1093/jpids/piw025

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We report the first case of a child in the United States infected with an organism producing a Verona Integron-Encoded Metallo-beta-Lactamase. This child succumbed to a ventilator-associated pneumonia caused by a Klebsiella pneumoniae producing this resistance mechanism.

引用

页码：E24 / E27

页数：4

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