Surgical Resection and Pazopanib Treatment for Recurrent Cardiac Angiosarcoma

被引：5

作者：

Nakamura, Yuki ^{[1
]}

Toda, Koichi ^{[1
]}

Miyagawa, Shigeru ^{[1
]}

Yoshikawa, Yasushi ^{[1
]}

Hata, Hiroki ^{[1
]}

Domae, Keitaro ^{[1
]}

Matsuura, Ryohei ^{[1
]}

Sawa, Yoshiki ^{[1
]}

机构：

[1] Osaka Univ, Grad Sch Med, Dept Cardiovasc Surg, 2-15 Yamada Oka, Suita, Osaka 5650871, Japan

来源：

CLINICAL PATHOLOGY | 2019年 / 12卷

关键词：

cardiac angiosarcoma; pazopanib; angiogenesis; SARCOMAS; OUTCOMES;

D O I：

10.1177/2632010X19831261

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Cardiac sarcoma treatment is challenging for surgeons because of frequent tumor recurrence and poor prognosis. In addition, optimal management of recurrences is not well established. The multi-targeted tyrosine kinase inhibitor, pazopanib, was recently approved for soft-tissue sarcoma. Herein, we present a case involving recurrent cardiac angiosarcoma where the patient survived for 2years with complete remission of disease after repeated surgical resection and treatment with oral pazopanib. Based on our experience, aggressive surgical resection combined with pazopanib may be a valid treatment for recurrent cardiac angiosarcoma to improve patient survival.

引用

页数：4

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