Metastatic epidural spinal cord compression

被引：271
作者：
Cole, John S. [1 ]
Patchell, Roy A. [1 ,2 ]
机构：
[1] Univ Kentucky, Med Ctr, Dept Neurosurg, Lexington, KY 40536 USA
[2] Univ Kentucky, Med Ctr, Dept Neurol, Lexington, KY 40536 USA
来源：
LANCET NEUROLOGY | 2008年 / 7卷 / 05期
关键词：
D O I：
10.1016/S1474-4422(08)70089-9
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Metastatic epidural spinal cord compression (MESCC) occurs when cancer metastasises to the spine or epidural space and causes secondary compression of the spinal cord. MESCC is a common complication of malignancy that affects almost 5% of patients with cancer. The most common symptom is back pain. MESCC is a medical emergency that needs rapid diagnosis and treatment if permanent paralysis is to be prevented: the diagnosis of MESCC is best made with MRI; and corticosteroids, radiation therapy, and surgery are all established treatments. Future research will focus on prevention, improving detection, and the development of new treatments.
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页码：459 / 466
页数：8
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