Fetal programming of the metabolic syndrome

被引：113

作者：

Marciniak, Aleksandra ^{[1
]}

Patro-Malysza, Jolanta ^{[1
]}

Kimber-Trojnar, Zaneta ^{[1
]}

Marciniak, Beata ^{[1
]}

Oleszczuk, Jan ^{[1
]}

Leszczynska-Gorzelak, Boena ^{[1
]}

机构：

[1] Med Univ Lublin, Dept Obstet & Perinatol, Jaczewskiego 8, PL-20954 Lublin, Poland

来源：

TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY | 2017年 / 56卷 / 02期

关键词：

fetal development; genetic predisposition to disease; metabolic syndrome X; nutritional status; pregnancy; LOW-BIRTH-WEIGHT; INSULIN-RESISTANCE; DIABETES-MELLITUS; POSTNATAL-GROWTH; MATERNAL OBESITY; FAMINE EXPOSURE; RESTRICTION; EXPRESSION; METHYLATION; DIET;

D O I：

10.1016/j.tjog.2017.01.001

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Prenatal development is currently recognized as a critical period in the etiology of human diseases. This is particularly so when an unfavorable environment interacts with a genetic predisposition. The fetal programming concept suggests that maternal nutritional imbalance and metabolic disturbances may have a persistent and intergenerational effect on the health of offspring and on the risk of diseases such as obesity, diabetes, and cardiovascular diseases. (C) 2017 Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V.

引用

页码：133 / 138

页数：6

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