Irreversible Electroporation in Locally Advanced Pancreatic Adenocarcinoma: Aiming to Improve Overall Survival

被引：0
作者：
Tristan Enjuto, Diego [1 ]
Herrera Merino, Norberto [1 ]
Abadal Villandrade, Jose Maria [2 ]
Galvez Gonzalez, Esther [2 ]
Llorente Lazaro, Rosa [1 ]
Diaz Pena, Patricia [1 ]
Alvarez Perez, Maria Jesus [2 ]
Perez Gonzalez, Marta [1 ]
机构：
[1] Hosp Univ Severo Ochoa, Gen & Digest Surg Dept, Avda Orellana S-N, Madrid 28911, Spain
[2] Hosp Univ Severo Ochoa, Intervent Radiol Dept, Leganes, Spain
来源：
JOURNAL OF GASTROINTESTINAL CANCER | 2020年 / 51卷 / 03期
关键词：
Locally advanced pancreatic cancer; Ablation techniques; Irreversible electroporation; SINGLE-INSTITUTION EXPERIENCE; CANCER; ABLATION; SAFETY;
D O I：
10.1007/s12029-020-00425-9
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Irreversible electroporation (IRE) is a non-thermic ablation therapy which has been proposed for locally advanced pancreatic adenocarcinoma (LAPC) as well as for the local control of other types of tumors (kidney or liver). Its use has been extended in the last few years worldwide. Its advantage over other ablation techniques is that it only affects the lipids bilayer of the cell membrane avoiding vascular damage. Safety and viability have been demonstrated in recent studies. Overall survival seems (OS) to improve when it is combined with chemotherapy compared to chemotherapy with or without radiotherapy. Clinical trials should confirm these encouraging data.
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收藏
页码：1084 / 1087
页数：4
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