Diagnosing COVID-19: The Disease and Tools for Detection

被引：1181

作者：

Udugama, Buddhisha ^{[2
,3
]}

Kadhiresan, Pranav ^{[2
,3
]}

Kozlowski, Hannah N. ^{[2
,3
]}

Malekjahani, Ayden ^{[2
,3
]}

Osborne, Matthew ^{[2
,3
]}

Li, Vanessa Y. C. ^{[2
,3
]}

Chen, Hongmin ^{[2
,3
]}

Mubareka, Samira ^{[4
,5
]}

Gubbay, Jonathan B. ^{[4
,6
,7
]}

Chan, Warren C. W. ^{[1
,2
,3
]}

机构：

[1] Univ Toronto, Inst Biomat & Biomed Engn, Terrence Donnelly Ctr Cellular & Biomol Res, Dept Chem & Mat Sci & Engn, Toronto, ON M5S 3G9, Canada

[2] Univ Toronto, Inst Biomat & Biomed Engn, Toronto, ON M5S 3G9, Canada

[3] Univ Toronto, Terrence Donnelly Ctr Cellular & Biomol Res, Toronto, ON M5S 3G9, Canada

[4] Univ Toronto, Dept Lab Med & Pathobiol, Fac Med, Toronto, ON M5S 1A1, Canada

[5] Sunnybrook Res Inst, Biol Sci, Toronto, ON M4N 3M5, Canada

[6] Publ Hlth Ontario, Toronto, ON M5G 1V2, Canada

[7] Hosp Sick Children, Toronto, ON M5G 1V2, Canada

来源：

ACS NANO | 2020年 / 14卷 / 04期

基金：

加拿大健康研究院; 加拿大自然科学与工程研究理事会; 瑞典研究理事会;

关键词：

SARS-CoV-2; diagnostics; COVID-19; PCR; surveillance; pandemic; OF-CARE DIAGNOSTICS; VIRUS-INFECTION; CORONAVIRUS; PCR; SARS; ASSAYS; SERUM; SENSITIVITY; POLYMERASE; PLATFORM;

D O I：

10.1021/acsnano.0c02624

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

COVID-19 has spread globally since its discovery in Hubei province, China in December 2019. A combination of computed tomography imaging, whole genome sequencing, and electron microscopy were initially used to screen and identify SARS-CoV-2, the viral etiology of COVID-19. The aim of this review article is to inform the audience of diagnostic and surveillance technologies for SARS-CoV-2 and their performance characteristics. We describe point-of-care diagnostics that are on the horizon and encourage academics to advance their technologies beyond conception. Developing plug-and-play diagnostics to manage the SARS-CoV-2 outbreak would be useful in preventing future epidemics.

引用

页码：3822 / 3835

页数：14

共 119 条

[1] Pilot use of a novel smartphone application to track traveller health behaviour and collect infectious disease data during a mass gathering: Hajj pilgrimage 2014 [J].

Alqahtani A.S. ;

BinDhim N.F. ;

Tashani M. ;

Willaby H.W. ;

Wiley K.E. ;

Heywood A.E. ;

Booy R. ;

Rashid H. .

Journal of Epidemiology and Global Health, 2016, 6 (3) :147-155

[2] A new approach for diagnosis of bovine coronavirus using a reverse transcription recombinase polymerase amplification assay [J].

Amer, H. M. ;

Abd El Wahed, A. ;

Shalaby, M. A. ;

Almajhdi, F. N. ;

Hufert, F. T. ;

Weidmann, M. .

JOURNAL OF VIROLOGICAL METHODS, 2013, 193 (02) :337-340

[3]

[Anonymous], 2020, REP WHO CHINA JOINT

[4]

[Anonymous], 2020, DET 2019 NOV COR 201

[5]

[Anonymous], 2020, TRANSMISSION EPIDEMI

[6]

[Anonymous], 2020, ESTIMATING NUMBER GL, DOI DOI 10.1101/2020.02.17.20024075

[7]

[Anonymous], DET COVID 19

[8]

[Anonymous], N ENGL J MED

[9]

[Anonymous], 2016, DISEASES-BASEL

[10]

[Anonymous], 2020, RAPID DETECTION NOVE, DOI DOI 10.1101/2020.02.19.20025155

← 1 2 3 4 5 6 7 8 9 10 →