Dynamic physiological temperature and pressure sensing with phase-resolved low-coherence interferometry

被引:10
|
作者
Coote, J. M. [1 ,2 ]
Alles, E. J. [1 ,2 ]
Noimark, S. [1 ,2 ,3 ]
Mosse, C. A. [1 ,2 ]
Little, C. D. [1 ,2 ,4 ]
Loder, C. D. [4 ]
David, A. L. [2 ,5 ]
Rakhit, R. D. [2 ,4 ]
Finlay, M. C. [1 ,2 ,6 ,7 ]
Desjardins, A. E. [1 ,2 ]
机构
[1] UCL, Dept Med Phys & Biomed Engn, Gower St, London WC1E 6BT, England
[2] UCL, Wellcome EPSRC Ctr Intervent & Surg Sci, Charles Bell House,43-45 Foley St, London W1W 7TS, England
[3] UCL, Mat Chem Res Ctr, Dept Chem, 20 Gordon St, London WC1H 0AJ, England
[4] Royal Free Hosp, Pond St, London NW3 2QG, England
[5] UCL, Inst Womens Hlth, 86-96 Chenies Mews, London WC1E 6HX, England
[6] St Bartholomews Hosp, Barts Heart Ctr, Charterhouse Sq, London EC1M 6BQ, England
[7] Queen Mary Univ London, Charterhouse Sq, London EC1M 6BQ, England
基金
英国惠康基金; 英国工程与自然科学研究理事会;
关键词
FABRY-PEROT SENSOR; FIBER SENSOR; IN-VIVO; SENSITIVITY; TOMOGRAPHY; RESOLUTION;
D O I
10.1364/OE.27.005641
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We report the development and characterisation of highly miniaturised fibre-optic sensors for simultaneous pressure and temperature measurement, and a compact interrogation system with a high sampling rate. The sensors, which have a maximum diameter of 250 mu m, are based on multiple low-finesse optical cavities formed from polydimethylsiloxane (PDMS), positioned at the distal ends of optical fibres, and interrogated using phase-resolved low-coherence interferometry. At acquisition rates of 250 Hz, temperature and pressure changes of 0.0021 degrees C and 0.22 mmHg arc detectable. An in vivo experiment demonstrated that the sensors had sufficient speed and sensitivity for monitoring dynamic physiological pressure waveforms. These sensors are ideally suited to various applications in minimally invasive surgery, where diminutive lateral dimensions, high sensitivity and low manufacturing complexities are particularly valuable. Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License.
引用
收藏
页码:5641 / 5654
页数:14
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