SYNTHESIS AND CHARACTERIZATION OF BIDENTATE CYCLOTRIPHOSPHAZENE DERIVATIVES

Three novel cyclotriphosphazene derivatives were designed. Title compounds were synthesized by the reaction of the dichlorocyclotriphosphazene derivative [N3P3Cl2(O2C12H8)(2)] with the potassium salt of 4-hydroxybenzaldehyde, and subsequent reduction of aldehyde groups to alcohol groups using sodium borohydride. The bromination reaction was carried out using PBr3 to give N3P3(O2C12H8)(2) (OC6H4-p-CH2Br)(2). This compound was employed in reactions with macrocyclic polyamide, imidazole, or morpholine to produce title compounds. The target compounds were characterized using H-1 NMR, P-31 NMR, C-13 NMR, IR, and electrospray ionization mass spectra (ESI-MS). [Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements for the following free supplemental resource: Figures S1-S6.]