In vivo Enhancement in Bioavailability of Atazanavir in the Presence of Proton-Pump Inhibitors using Mesoporous Materials

被引：39

作者：

Xia, Xin ^{[1
,3
]}

Zhou, Chunfang ^{[1
]}

Ballell, Lluis ^{[4
]}

Garcia-Bennett, Alfonso E. ^{[2
]}

机构：

[1] Nanol AB, S-11428 Stockholm, Sweden

[2] Uppsala Univ, Angstrom Lab, S-75121 Uppsala, Sweden

[3] Stockholm Univ, Dept Mat & Environm Chem, Arrhenius Lab, S-10691 Stockholm, Sweden

[4] GlaxoSmithKline, Dis Developing World, Madrid 28769, Spain

来源：

CHEMMEDCHEM | 2012年 / 7卷 / 01期

基金：

瑞典研究理事会;

关键词：

drug delivery; human immunodeficiency virus (HIV); mesoporous silica; proton-pump inhibitors; solubility; WATER-SOLUBLE DRUGS; DELIVERY; SOLUBILITY; RELEASE; PHASE; SUPERSATURATION; STABILIZATION; NANOPARTICLES; ITRACONAZOLE; PERMEATION;

D O I：

10.1002/cmdc.201100500

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：43 / 48

页数：6

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