Iridium-catalyzed transfer hydrogenation of nitroarenes to anilines

被引：41

作者：

Chen, Shujie ^{[1
]}

Lu, Guoping ^{[1
]}

Cai, Chun ^{[1
]}

机构：

[1] Nanjing Univ Sci & Technol, Sch Chem Engn, Nanjing 210094, Jiangsu, Peoples R China

来源：

NEW JOURNAL OF CHEMISTRY | 2015年 / 39卷 / 07期

关键词：

SUPPORTED GOLD NANOPARTICLES; NITRO-COMPOUNDS; CHEMOSELECTIVE REDUCTION; AROMATIC-AMINES; AMMONIA BORANE; COMPLEXES; NITROBENZENE; ACTIVATION; WATER; DEHYDROGENATION;

D O I：

10.1039/c5nj00917k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple and general homogeneous catalyst system composed of commercially available [Ir( cod)Cl](2) and 1,10-phenanthroline has been developed for the selective transfer hydrogenation of nitroarenes to anilines. It utilized the readily accessible 2-propanol as a hydrogen donor and had wide substrate scope. A careful mechanistic investigation through real-time detection and a series of controlled experiments with possible intermediates was also carried out, which showed that the transformation proceeds via both phenylhydroxylamine and azobenzene intermediates and the reduction of hydrazobenzene leading to aniline might be the rate-determining step.

引用

页码：5360 / 5365

页数：6