Building a neurocognitive profile of suicidal risk in severe mental disorders

被引:5
作者
Comparelli, Anna [1 ]
Corigliano, Valentina [2 ]
Montalbani, Benedetta [3 ]
Nardella, Adele [4 ]
De Carolis, Antonella [5 ]
Stampatore, Lorenzo [3 ]
Bargagna, Paride [3 ]
Forcina, Francesca [3 ]
Lamis, Dorian [6 ]
Pompili, Maurizio [1 ,7 ]
机构
[1] Sapienza Univ Rome, Azienda Osped Univ St Andrea, Via Grottarossa 1035, Rome, Italy
[2] Dept Psychiat Roma 1, Rome, Italy
[3] Sapienza Univ Rome, Fac Med & Psychol, Psychiat Residency Training Program, Rome, Italy
[4] Dept Psychiat & Subst Abuse, Modena, Italy
[5] Sapienza Univ, St Andrea Hosp, Unit Neurol Mental Hlth & Sensory Organs, Dept Neurosci, I-00185 Rome, Italy
[6] Emory Univ, Sch Med, Dept Psychiat & Behav Sci, Atlanta, GA USA
[7] Sapienza Univ, St Andrea Hosp, Dept Neurosci Mental Hlth & Sensory Organs, Suicide Prevent Ctr, I-00185 Rome, Italy
关键词
Suicide ideation; Suicide attempt; Neurocognition; Social cognition; MATRICS Consensus Cognitive Battery; CONSENSUS COGNITIVE BATTERY; SOCIAL COGNITION; IDEATION; BEHAVIOR; SCHIZOPHRENIA; SYMPTOMS; VERSION; MEMORY;
D O I
10.1186/s12888-022-04240-3
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Background Research on the influence of neurocognitive factors on suicide risk, regardless of the diagnosis, is inconsistent. Recently, suicide risk studies propose applying a trans-diagnostic framework in line with the launch of the Research Domain Criteria Cognitive Systems model. In the present study, we highlight the extent of cognitive impairment using a standardized battery in a psychiatric sample stratified for different degrees of suicidal risk. We also differentiate in our sample various neurocognitive profiles associated with different levels of risk. Materials and methods We divided a sample of 106 subjects into three groups stratified by suicide risk level: Suicide Attempt (SA), Suicidal Ideation (SI), Patient Controls (PC) and Healthy Controls (HC). We conducted a multivariate Analysis of Variance (MANOVA) for each cognitive domain measured through the standardized battery MATRICS Consensus Cognitive Battery (MCCB). Results We found that the group of patients performed worse than the group of healthy controls on most domains; social cognition was impaired in the suicide risk groups compared both to HC and PC. Patients in the SA group performed worse than those in the SI group. Conclusion Social cognition impairment may play a crucial role in suicidality among individuals diagnosed with serious mental illness as it is involved in both SI and SA; noteworthy, it is more compromised in the SA group fitting as a marker of risk severity.
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页数:8
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