Pd-catalyzed cascade cyclization of o-alkynylarylbromides with dialkylalkynes via consecutive carbopalladation

被引：3
|
作者：
Zhao, Jian [1 ]
Asao, Naoki [1 ]
Yamamoto, Yoshinori [1 ,2 ]
Jin, Tienan [1 ]
机构：
[1] Tohoku Univ, WPI Adv Inst Mat Res WPI AIMR, Sendai, Miyagi 9808577, Japan
[2] Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116023, Peoples R China
来源：
TETRAHEDRON LETTERS | 2015年 / 56卷 / 23期
关键词：
Cascade cyclization; Consecutive carbopalladation; Pd-catalyzed; o-Alkynylarylbromide; Dialkylalkyne; C-H ACTIVATION; TANDEM REACTIONS; DOMINO REACTIONS; CONSTRUCTION; ANNULATION; STRATEGIES;
D O I：
10.1016/j.tetlet.2014.12.023
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel Pd-catalyzed cascade cyclization of o-alkynylarylbromides with dialkylalkynes for the construction of the multisubstituted dihydrocyclopenta[a]indene derivatives has been reported. The reaction proceeds efficiently through a four consecutive carbopalladations with alkyne and alkene moieties. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码：3133 / 3136
页数：4
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