Candida auris: Epidemiology, risk factors, virulence, resistance, and therapeutic options

被引：86
作者：
Orlandi Sardi, Janaina de Cassia [1 ]
Silva, Diego Romario [1 ]
Soares Mendes-Giannini, Maria Jose [2 ]
Rosalen, Pedro Luiz [1 ]
机构：
[1] Univ Estadual Campinas, Dept Physiol Sci, Piracicaba Dent Sch, BR-13414903 Piracicaba, SP, Brazil
[2] Sao Paulo State Univ UNESP, Dept Clin Anal, Sch Pharmaceut Sci, BR-14800903 Araraquara, SP, Brazil
来源：
MICROBIAL PATHOGENESIS | 2018年 / 125卷
关键词：
Candida auris; Resistance; Virulence factor; FLIGHT MASS-SPECTROMETRY; CHANGING EPIDEMIOLOGY; HISTORICAL TRENDS; FUNGAL-INFECTIONS; BIOFILM FORMATION; IONIZATION-TIME; 1ST REPORT; IDENTIFICATION; DISINFECTANTS; MULTICENTER;
D O I：
10.1016/j.micpath.2018.09.014
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Candida awls emerged as a pathogen resistant to multiple antifungal and has been associated with nosocomial outbreaks with high transmission capacity between hospitalized individuals. C. auris was first described in 2009, after being isolated from the external ear canal discharge of a patient in Japan. The difficulty in identification, incorrect use of antifungal drugs, and treatment failure are causes of high mortality. Since then, C. auris has been increasingly reported from East Asia to North America, with substantial fatalities and misidentification. This review aims at describing the epidemiology, virulence, risk factors, resistance, and therapeutic options in C. auris infections.
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收藏
页码：116 / 121
页数：6
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