Using Precision Environmental Health Principles in Risk Evaluation and Communication of the Deepwater Horizon Oil Spill

被引:4
作者
Jackson, Daniel [1 ,7 ]
Huang, Meng [2 ,3 ]
Fernando, Harshica [4 ]
Ansari, Ghulam [5 ]
Howarth, Marilyn [2 ,3 ]
Mesaros, Clementina [2 ,3 ]
Penning, Trevor [2 ,3 ]
Elferink, Cornelis [1 ,6 ,7 ]
机构
[1] Univ Texas Med Branch, Dept Pharmacol & Toxicol, Galveston, TX 77555 USA
[2] Perelman Sch Med, Ctr Excellence Environm Toxicol, Philadelphia, PA USA
[3] Univ Penn, Dept Syst Pharmacol & Translat Therapeut, Philadelphia, PA 19104 USA
[4] Prairie View A&M Univ, Dept Chem, Prairie View, TX USA
[5] Univ Texas Med Branch, Dept Pathol, Galveston, TX 77555 USA
[6] Univ Texas Med Branch, Sealy Ctr Environm Hlth & Med, Galveston, TX 77555 USA
[7] Univ Penn, Dept Pathol, Sch Dent, Philadelphia, PA 19104 USA
基金
美国国家卫生研究院;
关键词
risk communication; Deepwater Horizon; seafood safety; POLYCYCLIC AROMATIC-HYDROCARBONS; POTENTIAL METABOLIC-ACTIVATION; SEAFOOD SAFETY; PAH; EXPOSURE; BIOASSAY;
D O I
10.1177/1048291118815606
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
This article provides a description of the rationale and processes adopted by the Gulf Coast Health Alliance: Health Risks related to the Macondo Spill consortium to evaluate and communicate the risk of exposure to polycyclic aromatic hydrocarbons (PAHs) in seafood over several years following the Deepwater Horizon disaster and subsequent oil spill. We examined gaps in knowledge associated with PAH toxicity following exposure to petrogenic (oil-derived) PAHs by studying the metabolic fate of PAHs and their potential toxicity using sophisticated analytical methods. Using the data generated, we developed a risk communication strategy designed to meet the needs of the stakeholder communities including a consumption guideline calculator, a web-based tool to reconcile seafood consumption with risk of adverse health effects.
引用
收藏
页码:599 / 616
页数:18
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