Background: Fibromyalgia syndrome (FMS) is a disorder characterized by widespread pain, tenderness, and fatigue. High prevalence marks the syndrome which is considered to reflect altered central pain processing. Fibromyalgia syndrome runs a chronic, non-progressive course, extracting high price owing to impaired quality of life, restricted vocational capacity, and increased health care utilization. Objective: To review current and emerging trends in the treatment of FMS. Methods: A rigorous search of published literature, abstract presentations, and industry provided data was performed. Results/conclusion: The recent FDA approval of pregabalin as a first specific medication for FMS may herald a new era for the development of medications with higher specificity and efficacy for this hitherto frustrating condition.
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Sheffield Hallam Univ, Fac Hlth & Wellbeing, Biomed Res Ctr, Sheffield S1 1WB, S Yorkshire, EnglandSheffield Hallam Univ, Fac Hlth & Wellbeing, Biomed Res Ctr, Sheffield S1 1WB, S Yorkshire, England
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University of Michigan, 1150 West Medical Center Drive, Ann Arbor, 48109-0680, MIUniversity of Michigan, 1150 West Medical Center Drive, Ann Arbor, 48109-0680, MI
Crofford L.J.
Appleton B.E.
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University of Michigan, 1150 West Medical Center Drive, Ann Arbor, 48109-0680, MIUniversity of Michigan, 1150 West Medical Center Drive, Ann Arbor, 48109-0680, MI
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Klinikum Saarbrucken, Dept Internal Med 1, D-66119 Saarbrucken, Germany
Tech Univ Munich, Dept Psychosomat Med & Psychotherapy, D-81675 Munich, GermanyKlinikum Saarbrucken, Dept Internal Med 1, D-66119 Saarbrucken, Germany
Haeuser, Winfried
Walitt, Brian
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George Washington Univ, Med Ctr, Washington Hosp Ctr, Washington, DC 20010 USAKlinikum Saarbrucken, Dept Internal Med 1, D-66119 Saarbrucken, Germany
Walitt, Brian
Fitzcharles, Mary-Ann
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McGill Univ, Ctr Hlth, Div Rheumatol, Montreal, PQ H3G 1A4, Canada
McGill Univ, Ctr Hlth, Alan Edwards Pain Management Unit, Montreal, PQ H3G 1A4, CanadaKlinikum Saarbrucken, Dept Internal Med 1, D-66119 Saarbrucken, Germany
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Liverpool John Moores Univ, Fac Hlth & Appl Social Sci, Liverpool L3 2AJ, Merseyside, EnglandLiverpool John Moores Univ, Fac Hlth & Appl Social Sci, Liverpool L3 2AJ, Merseyside, England
Hardy-Pickering, Robert
Adams, Nicola
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Liverpool John Moores Univ, Fac Hlth & Appl Social Sci, Hlth & Social Care, 79 Tithebarn St, Liverpool L2 2ER, Merseyside, EnglandLiverpool John Moores Univ, Fac Hlth & Appl Social Sci, Liverpool L3 2AJ, Merseyside, England
Adams, Nicola
Sim, Julius
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Keele Univ, Sch Hlth & Rehabil, Keele, Staffs, England
Keele Univ, Sch Hlth & Rehabil, Hlth Care Res, Keele ST5 5BG, Staffs, EnglandLiverpool John Moores Univ, Fac Hlth & Appl Social Sci, Liverpool L3 2AJ, Merseyside, England
Sim, Julius
Roe, Brenda
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Liverpool John Moores Univ, Fac Hlth & Appl Social Sci, Hlth Sci, Liverpool L2 2ER, Merseyside, EnglandLiverpool John Moores Univ, Fac Hlth & Appl Social Sci, Liverpool L3 2AJ, Merseyside, England
Roe, Brenda
Wallymahmed, Akhtar
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Liverpool John Moores Univ, Fac Hlth & Appl Social Sci, Liverpool L3 2AJ, Merseyside, EnglandLiverpool John Moores Univ, Fac Hlth & Appl Social Sci, Liverpool L3 2AJ, Merseyside, England