Further improvements of the synthesis of alkynes from aldehydes

被引：276

作者：

Roth, GJ ^{[1
]}

Liepold, B ^{[1
]}

Müller, SG ^{[1
]}

Bestmann, HJ ^{[1
]}

机构：

[1] Univ Erlangen Nurnberg, Inst Organ Chem, D-91054 Erlangen, Germany

来源：

SYNTHESIS-STUTTGART | 2004年 / 01期

关键词：

alkynes; phosphonates; rearrangements;

D O I：

10.1055/s-2003-44346

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly convenient way to perform the synthesis of alkynes from aldehydes is reported. The procedure utilizes a new in situ preparation of dimethyldiazomethylphosphonate. As a consequence a commercially available reagent can now be used, circumventing a disadvantage of earlier protocols. The easy one-pot procedure avoids the use of strong bases, low temperatures and inert gas techniques.

引用

页码：59 / 62

页数：4

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