Synthesis and Anti-MAO Activity of Alkylation Products of 2-Aminobenzamide, 2-Amino-1-(4-nitrophenyl)propane-1,3-diol, and Some Amino Acids with Mono- and Bis-β-aminoketones

被引：0

作者：

Akopyan, N. Z. ^{[1
]}

Agababyan, A. G. ^{[1
]}

Ovasyan, Z. A. ^{[1
]}

Isakhanyan, A. U. ^{[1
]}

Grigoryan, A. S. ^{[1
]}

Navoyan, K. G. ^{[1
]}

Gasparyan, G., V ^{[1
]}

Panosyan, H. A. ^{[1
]}

机构：

[1] Natl Acad Sci Republ Armenia, Sci & Technol Ctr Organ & Pharmaceut Chem, Yerevan 0014, Armenia

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2022年 / 92卷 / 06期

关键词：

beta-aminoketones; bis-beta-amino ketones; alkylation; 2-aminobenzamide; amino acids; 2-amino-1-(4-nitrophenyl)propane-1,3-diol; anti-MAO activity;

D O I：

10.1134/S1070363222060019

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reactions of substituted 3-(diethylamino)propan-1-ones hydrochlorides with 2-aminobenzamide, 2-amino-1-(4-nitrophenyl)propane-1,3-diol and some amino acids afforded the corresponding beta-amino-ketones. 2,2'-{1,omega-alkane -diylbis[oxy-4, 1-pheny lene (3-oxo-3,1-propanediyl)imino]} bisbenzamides were synthesized in the same way. Anti-MAO activity of the synthesized compounds was studied.

引用

页码：925 / 931

页数：7