Synthesis and Anti-MAO Activity of Alkylation Products of 2-Aminobenzamide, 2-Amino-1-(4-nitrophenyl)propane-1,3-diol, and Some Amino Acids with Mono- and Bis-β-aminoketones

被引：0

作者：

Akopyan, N. Z. ^{[1
]}

Agababyan, A. G. ^{[1
]}

Ovasyan, Z. A. ^{[1
]}

Isakhanyan, A. U. ^{[1
]}

Grigoryan, A. S. ^{[1
]}

Navoyan, K. G. ^{[1
]}

Gasparyan, G., V ^{[1
]}

Panosyan, H. A. ^{[1
]}

机构：

[1] Natl Acad Sci Republ Armenia, Sci & Technol Ctr Organ & Pharmaceut Chem, Yerevan 0014, Armenia

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2022年 / 92卷 / 06期

关键词：

beta-aminoketones; bis-beta-amino ketones; alkylation; 2-aminobenzamide; amino acids; 2-amino-1-(4-nitrophenyl)propane-1,3-diol; anti-MAO activity;

D O I：

10.1134/S1070363222060019

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reactions of substituted 3-(diethylamino)propan-1-ones hydrochlorides with 2-aminobenzamide, 2-amino-1-(4-nitrophenyl)propane-1,3-diol and some amino acids afforded the corresponding beta-amino-ketones. 2,2'-{1,omega-alkane -diylbis[oxy-4, 1-pheny lene (3-oxo-3,1-propanediyl)imino]} bisbenzamides were synthesized in the same way. Anti-MAO activity of the synthesized compounds was studied.

引用

页码：925 / 931

页数：7

共 17 条

[1] Synthesis and Anti-MAO Activity of Alkylation Products of 2-Aminobenzamide, 2-Amino-1-(4-nitrophenyl)propane-1,3-diol, and Some Amino Acids with Mono- and Bis-β-aminoketones
N. Z. Akopyan
A. G. Agababyan
Z. A. Ovasyan
A. U. Isakhanyan
A. S. Grigoryan
K. G. Navoyan
G. V. Gasparyan
H. A. Panosyan
Russian Journal of General Chemistry, 2022, 92 : 925 - 931
[2] RESOLUTION OF THE ENANTIOMERS OF (S,R)-1,1'-BI-2,2'-NAPHTHYLHYDROGENPHOSPHATE BY (1R,2R)-2-AMINO-1-(4-NITROPHENYL)-PROPANE-1,3-DIOL AND (1S,2S)-2-AMINO-1-(4-NITROPHENYL)-PROPANE-1,3-DIOL
WERNER, W
TRESSELT, D
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JOURNAL FUR PRAKTISCHE CHEMIE, 1987, 329 (06): : 1031 - 1037
[3] Electroreduction of (1S,2S)-2-amino-1-(4-nitrophenyl)-propane-1,3-diol derivatives.: Behaviour of electrogenerated species and applications to organic synthesis
Cristea, CV
Moinet, C
Jitaru, M
Darabantu, M
JOURNAL OF APPLIED ELECTROCHEMISTRY, 2005, 35 (09) : 845 - 849
[4] Electroreduction of (1S,2S)-2-amino-1-(4-nitrophenyl)-propane-1,3-diol derivatives. Behaviour of electrogenerated species and applications to organic synthesis
C.V. Cristea
C. Moinet
M. JITARU
M. Darabantu
Journal of Applied Electrochemistry, 2005, 35 : 845 - 849
[5] (1S*,2S*)-(+)-2-amino-1-[4-(methylsulfanyl)phenyl]propane-1,3-diol
Samas, B
Macikenas, D
Blackburn, AC
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2005, 61 : O2793 - O2794
[6] Novel N-modified glycines based on a (1S,2S)-2-amino-1-(4-nitrophenyl) propane-1,3-diol skeleton: 1,3-dioxanes and tripodands
Moldovan, Oana
Albert, Katalin
Nagy, Iulia
Morar, Cristina
Sacalis, Carmen
Darabantu, Mircea
TETRAHEDRON LETTERS, 2016, 57 (51) : 5808 - 5811
[7] ELECTROCHEMICAL AND ANTIBACTERIAL BEHAVIOR OF DERIVATIVES OF (1S, 2S) - 2 AMINO- 1- (4-NITROPHENYL) - PROPANE-1,3-DIOL
Cristea, Cecilia
Voiculescu, G.
Jitaru, Maria
Moinet, C.
SCIENTIFIC STUDY AND RESEARCH-CHEMISTRY AND CHEMICAL ENGINEERING BIOTECHNOLOGY FOOD INDUSTRY, 2006, 7 (01): : 209 - 216
[8] Electrosynthesis of nitroso compounds from (1S, 2S)-2-amino-l-(4-nitrophenyl)-propane-1,3-diol derivatives
C. V. Cristea
C. Moinet
M. Jitaru
I. C. Popescu
Journal of Applied Electrochemistry, 2005, 35 : 851 - 855
[9] Electrosynthesis of nitroso compounds from (1S,2S)-2-amino-l-(4-nitrophenyl)-propane-1,3-diol derivatives
Cristea, CV
Moinet, C
Jitaru, M
Popescu, IC
JOURNAL OF APPLIED ELECTROCHEMISTRY, 2005, 35 (09) : 851 - 855
[10] Study of chiral β-enaminones prepared from pyrrolidine, cytisine, salsoline and 2-amino-1-(4-nitrophenyl)propane-1,3-diol:: resolution of salsoline via diastereomeric modified carane-type β-enaminones
Popov, SA
Gatilov, YV
Rybalova, TV
Tkachev, AV
TETRAHEDRON-ASYMMETRY, 2003, 14 (02) : 233 - 238

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