Bioassay-guided isolation of antimicrobial benzopyrans and phloroglucinol derivatives from Hypericum species

被引:27
作者
Dall'Agnol, R [1 ]
Ferraz, A [1 ]
Bernardi, AP [1 ]
Albring, D [1 ]
Nör, C [1 ]
Schapoval, EES [1 ]
von Poser, GL [1 ]
机构
[1] Univ Fed Rio Grande do Sul, Fac Farm, Programa Pos Grad Ciencias Farmaceut, BR-90610000 Porto Alegre, RS, Brazil
关键词
Staphylococcus aureus; bioautography; antibacterial; polyphenolic compounds; natural products;
D O I
10.1002/ptr.1546
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Recently the crude methanol extracts of six Hypericum species were analysed against a panel of microorganisms and it was found that H. caprifoliatum Cham. & Schlecht., H. myrianthum Cham. & Schlecht. and H. polyanthemum Klotzsch ex Reichardt were the most active. This paper reports the activity of the hexane, chloroform and methanol fractions of these plants as well as the activity of some isolated compounds against Staphylococcus aureus determined by bioautographic procedures. Copyright (c) 2005 John Wiley & Sons, Ltd.
引用
收藏
页码:291 / 293
页数:3
相关论文
共 16 条
  • [1] [Anonymous], 1988, FARMACOPEIA BRASILEI
  • [2] [Anonymous], CAD FARM
  • [3] Antimicrobial activity of some Hypericum species
    Dall'Agnol, R
    Ferraz, A
    Bernardi, AP
    Albring, D
    Nör, C
    Sarmento, L
    Lamb, L
    Hass, M
    von Poser, G
    Schapoval, EES
    [J]. PHYTOMEDICINE, 2003, 10 (6-7) : 511 - 516
  • [4] Uliginosin B from Hypericum myrianthum
    Ferraz, ABF
    Schripsema, J
    Pohlmann, AR
    von Poser, GL
    [J]. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2002, 30 (10) : 989 - 991
  • [5] Benzopyrans from Hypericum polyanthemum
    Ferraz, ABF
    Bordignon, SAL
    Staats, C
    Schripsema, J
    von Poser, GL
    [J]. PHYTOCHEMISTRY, 2001, 57 (08) : 1227 - 1230
  • [6] Antibiotic resistance
    Finch, RG
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1998, 42 (02) : 125 - 128
  • [7] ISHIGURO K, 1986, PLANTA MED, P288, DOI 10.1055/s-2007-969154
  • [8] SAROASPIDIN-A, SAROASPIDIN-B, AND SAROASPIDIN-C - ADDITIONAL ANTIBIOTIC COMPOUNDS FROM HYPERICUM-JAPONICUM
    ISHIGURO, K
    YAMAKI, M
    KASHIHARA, M
    TAKAGI, S
    [J]. PLANTA MEDICA, 1987, (05) : 415 - 417
  • [9] NEW ANTIMICROBIAL FILICINIC ACID-DERIVATIVES FROM HYPERICUM-DRUMMONDII
    JAYASURIYA, H
    CLARK, AM
    MCCHESNEY, JD
    [J]. JOURNAL OF NATURAL PRODUCTS, 1991, 54 (05): : 1314 - 1320
  • [10] Screening seeds of Scottish plants for antibacterial activity
    Kumarasamy, Y
    Cox, PJ
    Jaspars, M
    Nahar, L
    Sarker, SD
    [J]. JOURNAL OF ETHNOPHARMACOLOGY, 2002, 83 (1-2) : 73 - 77