Triterpenoid Saponins from Symplocos lancifolia

被引：70

作者：

Acebey-Castellon, Ivone Lucia ^{[1
]}

Voutquenne-Nazabadioko, Laurence ^{[1
]}

Huong Doan Thi Mai ^{[2
]}

Roseau, Nathalie ^{[1
]}

Bouthagane, Naima ^{[1
]}

Muhammad, Dima ^{[1
]}

Debar, Elisabeth Le Magrex ^{[3
]}

Gangloff, Sophie C. ^{[3
]}

Litaudon, Marc ^{[4
]}

Sevenet, Thierry ^{[4
]}

Nguyen Van Hung ^{[2
]}

Lavaud, Catherine ^{[1
]}

机构：

[1] CNRS, ICMR, Grp Isolement & Struct, UMR 6229, F-51687 Reims, France

[2] Acad Sci & Technol Vietnam, Inst Chim, Hanoi, Vietnam

[3] UFR Pharm, IFR 53, EA 4303, Lab Immunol & Microbiol, F-51096 Reims, France

[4] CNRS, Inst Chim Subst Nat, Ctr Rech Gif, F-91198 Gif Sur Yvette, France

来源：

JOURNAL OF NATURAL PRODUCTS | 2011年 / 74卷 / 02期

关键词：

C-13; NMR-SPECTRA; PENTACYCLIC TRITERPENOIDS; ANTIBACTERIAL ACTIVITY; RACEMOSA; PLANTS; ACIDS; CONSTITUENTS; DERIVATIVES; GLYCOSIDES;

D O I：

10.1021/np100502y

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new bidesmosidic saponins (1-3) and a new ursane triterpenoid, 2 alpha,3 beta,11 alpha,23-tetrahydroxyurs-12-en-28-oic acid (4), along with seven known compounds, were isolated from a methanolic extract, of the leaves of Symplocos lancifolia. The bidesmosidic saponins were found to possess the same sugar unit part, composed of two beta-D-glucose moieties and one alpha-L-rhamnose Moiety, linked to maslinic add, arjunolic acid, and asiatic acid, respectively. Their structures were elucidated by interpretation of their ID and 2D NMR spectra and completed by analysis of the HRESIMS data. The e antibacterial activity of the isolated triterpenoids was evaluated against Staphylococcus minus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa, and several showed activity against Gram-positive bacteria.

引用

页码：163 / 168

页数：6

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