Microwave-Promoted Selective Mono-N-Alkylation of Anilines with Tertiary Amines by Heterogeneous Catalysis

被引：43
作者：
Lubinu, M. Caterina [1 ]
De Luca, Lidia [1 ]
Giacomelli, Giampaolo [1 ]
Porcheddu, Andrea [1 ]
机构：
[1] Univ Sassari, Dipartimento Chim, I-07100 Sassari, Italy
来源：
CHEMISTRY-A EUROPEAN JOURNAL | 2011年 / 17卷 / 01期
关键词：
alkylation; amines; anilines; heterogeneous catalysis; microwave chemistry; BORROWING HYDROGEN; C-C; PALLADIUM CATALYSTS; EXCHANGE-REACTION; ARYL IODIDES; EFFICIENT; ALCOHOLS; STRATEGY; CARBON; SUZUKI;
D O I：
10.1002/chem.201002704
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A palladium-catalyzed N-alkylation of anilines with tertiary amines that occurs under heterogeneous transfer-hydrogenation conditions has been developed (see scheme). This protocol of transamination, which uses a relatively cheap and easily recyclable heterogeneous catalyst, can be efficiently applied to different substrates and is suitable for large-scale preparations. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：82 / 85
页数：4
相关论文
共 44 条
  • [1] Reductive amination of aldehydes and ketones with sodium triacetoxyborohydride. Studies on direct and indirect reductive amination procedures
    AbdelMagid, AF
    Carson, KG
    Harris, BD
    Maryanoff, CA
    Shah, RD
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (11) : 3849 - 3862
  • [2] [Anonymous], 2008, ANGEW CHEM INT EDIT
  • [3] [Anonymous], 2007, AM ETHNOL
  • [4] Ruthenium-catalyzed synthesis of secondary alkylamines:: Selective alkylation with aliphatic amines
    Baehn, Sebastian
    Hollmann, Dirk
    Tillack, Annegret
    Beller, Matthias
    [J]. ADVANCED SYNTHESIS & CATALYSIS, 2008, 350 (13) : 2099 - 2103
  • [5] Selective Ruthenium-Catalyzed N-Alkylation of Indoles by Using Alcohols
    Baehn, Sebastian
    Imm, Sebastian
    Mevius, Kathleen
    Neubert, Lorenz
    Tillack, Annegret
    Williams, Jonathan M. J.
    Beller, Matthias
    [J]. CHEMISTRY-A EUROPEAN JOURNAL, 2010, 16 (12) : 3590 - 3593
  • [6] C-C, C-O, C-N bond formation on sp2 carbon by Pd(II)-catalyzed reactions involving oxidant agents
    Beccalli, Egle M.
    Broggini, Gianluigi
    Martinelli, Michela
    Sottocornola, Silvia
    [J]. CHEMICAL REVIEWS, 2007, 107 (11) : 5318 - 5365
  • [7] Synthesis of Benzazoles by Hydrogen-Transfer Catalysis
    Blacker, A. John
    Farah, Mohamed M.
    Hall, Michael I.
    Marsden, Stephen P.
    Saidi, Ourida
    Williams, Jonathan M. J.
    [J]. ORGANIC LETTERS, 2009, 11 (09) : 2039 - 2042
  • [8] Dehydrogenation as a Substrate-Activating Strategy in Homogeneous Transition-Metal Catalysis
    Dobereiner, Graham E.
    Crabtree, Robert H.
    [J]. CHEMICAL REVIEWS, 2010, 110 (02) : 681 - 703
  • [9] The art of meeting palladium specifications in active pharmaceutical ingredients produced by Pd-catalyzed reactions
    Garrett, CE
    Prasad, K
    [J]. ADVANCED SYNTHESIS & CATALYSIS, 2004, 346 (08) : 889 - 900
  • [10] Asymmetric transfer hydrogenation: chiral ligands and applications
    Gladiali, S
    Alberico, E
    [J]. CHEMICAL SOCIETY REVIEWS, 2006, 35 (03) : 226 - 236
12345