Microwave-Promoted Selective Mono-N-Alkylation of Anilines with Tertiary Amines by Heterogeneous Catalysis

被引:44
作者
Lubinu, M. Caterina [1 ]
De Luca, Lidia [1 ]
Giacomelli, Giampaolo [1 ]
Porcheddu, Andrea [1 ]
机构
[1] Univ Sassari, Dipartimento Chim, I-07100 Sassari, Italy
关键词
alkylation; amines; anilines; heterogeneous catalysis; microwave chemistry; BORROWING HYDROGEN; C-C; PALLADIUM CATALYSTS; EXCHANGE-REACTION; ARYL IODIDES; EFFICIENT; ALCOHOLS; STRATEGY; CARBON; SUZUKI;
D O I
10.1002/chem.201002704
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A palladium-catalyzed N-alkylation of anilines with tertiary amines that occurs under heterogeneous transfer-hydrogenation conditions has been developed (see scheme). This protocol of transamination, which uses a relatively cheap and easily recyclable heterogeneous catalyst, can be efficiently applied to different substrates and is suitable for large-scale preparations. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:82 / 85
页数:4
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