Microwave-Promoted Selective Mono-N-Alkylation of Anilines with Tertiary Amines by Heterogeneous Catalysis

被引：44

作者：

Lubinu, M. Caterina ^{[1
]}

De Luca, Lidia ^{[1
]}

Giacomelli, Giampaolo ^{[1
]}

Porcheddu, Andrea ^{[1
]}

机构：

[1] Univ Sassari, Dipartimento Chim, I-07100 Sassari, Italy

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2011年 / 17卷 / 01期

关键词：

alkylation; amines; anilines; heterogeneous catalysis; microwave chemistry; BORROWING HYDROGEN; C-C; PALLADIUM CATALYSTS; EXCHANGE-REACTION; ARYL IODIDES; EFFICIENT; ALCOHOLS; STRATEGY; CARBON; SUZUKI;

D O I：

10.1002/chem.201002704

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A palladium-catalyzed N-alkylation of anilines with tertiary amines that occurs under heterogeneous transfer-hydrogenation conditions has been developed (see scheme). This protocol of transamination, which uses a relatively cheap and easily recyclable heterogeneous catalyst, can be efficiently applied to different substrates and is suitable for large-scale preparations. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：82 / 85

页数：4

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