Pinched flow fractionation for rapid and continuous particle separation in microfluidic devices

被引：0

作者：

Yamada, M ^{[1
]}

Nakashima, M ^{[1
]}

Sai, Y ^{[1
]}

Yasuda, M ^{[1
]}

Seki, M ^{[1
]}

机构：

[1] Univ Tokyo, Sch Engn, Dept Chem & Biotechnol, Bunkyo Ku, Tokyo 1138656, Japan

来源：

Micro Total Analysis Systems 2004, Vol 1 | 2005年 / 296期

关键词：

pinched flow fractionation; particle; separation; microfluidics;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We have demonstrated a new method for particle separation, named 'pinched flow fractionation (PFF)', in microfluidic devices. In this method, particles can be separated continuously according to their sizes, utilizing a laminar flow profile inside a pinched microchannel. First, we performed collection of separated particles using multi-branched microchannel, and next, small size particles (similar to 1 mu m in diameter) were successfully separated using a downsized microchannel. From the results obtained, we have successfully demonstrated that this method is highly applicable for the separation of various kinds of particles. Also it was demonstrated that this method can be applicable not just to particle size analysis, but to preparation of monodispersed particles.

引用

页码：414 / 416

页数：3