Two Zinc(II) and Nickel(II)-based Complexes: Anti Breast Cancer Activity

被引：6

作者：

Cui, Li-Jing ^{[1
]}

Zhang, Bin ^{[2
]}

Liu, Chun-Yan ^{[3
]}

Bian, Ming ^{[3
]}

机构：

[1] Guangdong Food & Drug Vocat Coll, Sch Pharm, Guangzhou, Guangdong, Peoples R China

[2] Inner Mongolia Univ Nationalities, Clin Med Coll 1, Tongliao, Inner Mongolia, Peoples R China

[3] Inner Mongolia Univ Nationalities, Med Chem & Pharmacol Inst, Tongliao, Inner Mongolia, Peoples R China

来源：

ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE | 2017年 / 643卷 / 17期

基金：

中国国家自然科学基金;

关键词：

Coordination polymer; Solvothermal condition; Breast cancer; Zinc; Nickel; CRYSTAL;

D O I：

10.1002/zaac.201700190

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Two zinc(II) and nickel(II) based coordination polymers, {[Zn(bibp)(MoO4)](H2O)(2)}(n) (1) [bibp = 4,4-bis(imidazol-1-yl)-biphenyl] and [Ni-2(CN)(4)(phen)(2)](n) (2) (phen = 1,10-phenanthroline), were synthesized and structurally characterized under solvothermal conditions. Compound 1 can be viewed as the connection of the 1D W-type chain [Zn(trans-bibp)] with the MoO42- anion to form a uninodal 4-connected net, whereas 2 features one-dimensional Ni-II cyanide chains decorated either with linear Ni(CN)(4) side chains or with 1,10-phenanthroline ligands bound directly to the Ni-II sites of the parent chain. In addition, in vitro anticancer activities of compounds 1 and 2 on four human breast cancer cells (MDA-MB-231, MDA-MB-468, SK-BR-3, and MCF7) was further determined.

引用

页码：1139 / 1142

页数：4

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