Safety, pharmacokinetics, and pharmacodynamics of Dapagliflozin (BMS-512148) in an ascending, placebo-controlled, multiple-dose study in healthy adult subjects

被引：0
|
作者：
Brenner, E. [1 ]
Komoroski, B. [1 ]
Boulton, D. [1 ]
Li, L. [1 ]
机构：
[1] Bristol Myers Squibb Co, Princeton, NJ 08543 USA
来源：
DIABETOLOGIA | 2007年 / 50卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
0765
引用
收藏
页码：S316 / S316
页数：1
相关论文
共 50 条
  • [1] Safety, pharmacokinetics, and pharmacodynamics of Dapagliflozin (BMS-512148), a selective SGLT2 inhibitor, in an ascending, placebo-controlled, single-dose study in healthy adult subjects
    Li, L.
    Komoroski, B.
    Boulton, D.
    Brenner, E.
    Vachharajani, N.
    Kornhauser, D.
    DIABETOLOGIA, 2007, 50 : S315 - S315
  • [2] A Placebo-Controlled, Multiple Ascending Dose Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of Avagacestat (BMS-708163) in Healthy Young and Elderly Subjects
    Dockens, Randy
    Wang, Jun-Sheng
    Castaneda, Lorna
    Sverdlov, Oleksandr
    Huang, Shu-Pang
    Slemmon, Randy
    Gu, Huidong
    Wong, Oi
    Li, Hewei
    Berman, Robert M.
    Smith, Christina
    Albright, Charles F.
    Tong, Gary
    CLINICAL PHARMACOKINETICS, 2012, 51 (10) : 681 - 693
  • [3] A Placebo-Controlled, Multiple Ascending Dose Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of Avagacestat (BMS-708163) in Healthy Young and Elderly Subjects
    Randy Dockens
    Jun-Sheng Wang
    Lorna Castaneda
    Oleksandr Sverdlov
    Shu-Pang Huang
    Randy Slemmon
    Huidong Gu
    Oi Wong
    Hewei Li
    Robert M. Berman
    Christina Smith
    Charles F. Albright
    Gary Tong
    Clinical Pharmacokinetics, 2012, 51 : 681 - 693
  • [4] Evaluation of safety and tolerability, pharmacokinetics, and pharmacodynamics of BMS-820836 in healthy subjects: a placebo-controlled, ascending single-dose study
    Risinger, Robert
    Bhagwagar, Zubin
    Luo, Feng
    Cahir, Matthew
    Miler, Laura
    Mendonza, Anisha E.
    Meyer, Jeffrey H.
    Zheng, Ming
    Hayes, Wendy
    PSYCHOPHARMACOLOGY, 2014, 231 (11) : 2299 - 2310
  • [5] Evaluation of safety and tolerability, pharmacokinetics, and pharmacodynamics of BMS-820836 in healthy subjects: a placebo-controlled, ascending single-dose study
    Robert Risinger
    Zubin Bhagwagar
    Feng Luo
    Matthew Cahir
    Laura Miler
    Anisha E. Mendonza
    Jeffrey H. Meyer
    Ming Zheng
    Wendy Hayes
    Psychopharmacology, 2014, 231 : 2299 - 2310
  • [6] Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of macitentan, an Endothelin Receptor Antagonist, in an Ascending Multiple-Dose Study in Healthy Subjects
    Sidharta, Patricia N.
    van Giersbergen, Paul L. M.
    Dingemanse, Jasper
    JOURNAL OF CLINICAL PHARMACOLOGY, 2013, 53 (11): : 1131 - 1138
  • [7] A phase I, randomized, double-blind, placebo-controlled, ascending single- and multiple-dose study of the pharmacokinetics, safety, and tolerability of oral ceftibuten in healthy adult subjects
    Hernandez-Mitre, Maria Patricia
    Wallis, Steven C.
    Morgan, Elizabeth E.
    Dudley, Michael N.
    Loutit, Jeffery S.
    Griffith, David C.
    Roberts, Jason A.
    Shields, Ryan K.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2024, 68 (01)
  • [8] A Randomized, Placebo-Controlled, Multiple-Ascending-Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Soluble Guanylate Cyclase Stimulator Praliciguat in Healthy Subjects
    Hanrahan, John P.
    Wakefield, James D.
    Wilson, Phebe J.
    Mihova, Marina
    Chickering, Jennifer G.
    Ruff, Dennis
    Hall, Michael
    Milne, G. Todd
    Currie, Mark G.
    Profy, Albert T.
    CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2019, 8 (05): : 564 - 575
  • [9] Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Alirocumab in Healthy Chinese Subjects: A Randomized, Double-Blind, Placebo-Controlled, Ascending Single-Dose Study
    Haiyan Li
    Yudong Wei
    Zhenhua Yang
    Shuang Zhang
    Xiuxiu Xu
    Mengmeng Shuai
    Olivier Vitse
    Yiwen Wu
    Marie T. Baccara-Dinet
    Yi Zhang
    Jianyong Li
    American Journal of Cardiovascular Drugs, 2020, 20 : 489 - 503
  • [10] Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Alirocumab in Healthy Chinese Subjects: A Randomized, Double-Blind, Placebo-Controlled, Ascending Single-Dose Study
    Li, Haiyan
    Wei, Yudong
    Yang, Zhenhua
    Zhang, Shuang
    Xu, Xiuxiu
    Shuai, Mengmeng
    Vitse, Olivier
    Wu, Yiwen
    Baccara-Dinet, Marie T.
    Zhang, Yi
    Li, Jianyong
    AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS, 2020, 20 (05) : 489 - 503
12345