Induction of prolactin receptors in cholangiocytes of male and female rats after ligation of the common bile duct

被引：14

作者：

Smirnova, OV ^{[1
]}

Petrashchuk, OM ^{[1
]}

Smirnov, AN ^{[1
]}

机构：

[1] Moscow MV Lomonosov State Univ, Fac Biol, Dept Endocrinol, Moscow 117234, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1998年 / 125卷 / 01期

基金：

俄罗斯基础研究基金会;

关键词：

prolactin receptors; immunohistochemistry; rat cholangiocytes; proliferation; sex hormones;

D O I：

10.1007/BF02496802

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Intense expression of prolactin receptors in cholangiocyte nuclei, nuclear membranes, and cytoplasm was demonstrated by the indirect immunoperoxidase method in intact and gonadectomied male and female rats after ligation of the common bile duct, The intensity of staining increased during cholangiocyte proliferative response to the intervention and, in contrast to hepatocytes, did not depend on animal sex and the presence of the gonads.

引用

页码：56 / 60

页数：5

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