A finite element method approach for the mechanobiological modeling of the osseointegration of a dental implant

被引：30
作者：
Vanegas-Acosta, J. C. [1 ,2 ]
Landinez P, N. S. [4 ]
Garzon-Alvarado, D. A. [2 ]
Casale R, M. C. [3 ]
机构：
[1] Univ Nacl Colombia, Grp Math Modeling & Numer Methods GNUM UN, Off 103A, Fac Engn, Bogota, Colombia
[2] Univ Nacl Colombia, Dept Mech & Mechatron Engn, Bogota, Colombia
[3] Univ Nacl Colombia, Fac Odontol, Div & Lab Orthodont, Bogota, Colombia
[4] Univ Nacl Colombia, Fac Med, Dept Human Corporal Movement, Bogota, Colombia
来源：
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE | 2011年 / 101卷 / 03期
关键词：
Dental implant; Osseointegration; Mathematical modeling; Mechanobiology; ELECTRON-MICROSCOPY; PATTERN-FORMATION; IN-VITRO; BONE; TITANIUM; FIBRIN; SURFACE; TISSUE; CELLS; REGENERATION;
D O I：
10.1016/j.cmpb.2010.11.007
中图分类号：
TP39 [计算机的应用];
学科分类号：
081203 ; 0835 ;
摘要：
The aim of this paper is to introduce a new mathematical model using a mechanobiological approach describing the process of osseointegration at the bone-derrcal implant interface in terms of biological and mechanical factors and the implant surface. The model has been computationally implemented by using the finite element method. The results show the spatial-temporal patterns distribution at the bone-dental implant interface and demonstrate the ability of the model to reproduce features of the wound healing process such as blood clotting, osteogenic cell migration, granulation tissue formation, collagen-like matrix displacements and new osteoid formation. The model might be used as a methodological basis for designing a dental tool useful to predict the degree of osseointegration of dental implants and subsequent formulation of mathematical models associated with different types of bone injuries and different types of implantable devices. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：297 / 314
页数：18
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