A finite element method approach for the mechanobiological modeling of the osseointegration of a dental implant

被引：30

作者：

Vanegas-Acosta, J. C. ^{[1
,2
]}

Landinez P, N. S. ^{[4
]}

Garzon-Alvarado, D. A. ^{[2
]}

Casale R, M. C. ^{[3
]}

机构：

[1] Univ Nacl Colombia, Grp Math Modeling & Numer Methods GNUM UN, Off 103A, Fac Engn, Bogota, Colombia

[2] Univ Nacl Colombia, Dept Mech & Mechatron Engn, Bogota, Colombia

[3] Univ Nacl Colombia, Fac Odontol, Div & Lab Orthodont, Bogota, Colombia

[4] Univ Nacl Colombia, Fac Med, Dept Human Corporal Movement, Bogota, Colombia

来源：

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE | 2011年 / 101卷 / 03期

关键词：

Dental implant; Osseointegration; Mathematical modeling; Mechanobiology; ELECTRON-MICROSCOPY; PATTERN-FORMATION; IN-VITRO; BONE; TITANIUM; FIBRIN; SURFACE; TISSUE; CELLS; REGENERATION;

D O I：

10.1016/j.cmpb.2010.11.007

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

The aim of this paper is to introduce a new mathematical model using a mechanobiological approach describing the process of osseointegration at the bone-derrcal implant interface in terms of biological and mechanical factors and the implant surface. The model has been computationally implemented by using the finite element method. The results show the spatial-temporal patterns distribution at the bone-dental implant interface and demonstrate the ability of the model to reproduce features of the wound healing process such as blood clotting, osteogenic cell migration, granulation tissue formation, collagen-like matrix displacements and new osteoid formation. The model might be used as a methodological basis for designing a dental tool useful to predict the degree of osseointegration of dental implants and subsequent formulation of mathematical models associated with different types of bone injuries and different types of implantable devices. (C) 2010 Elsevier Ireland Ltd. All rights reserved.

引用

页码：297 / 314

页数：18

共 97 条

[1]

ADELL R, 1970, Scandinavian Journal of Plastic and Reconstructive Surgery, V4, P19

[2]

ADELL R, 1981, ORAL SURG, V10, P387

[3] Osteoinduction, osteoconduction and osseointegration [J].

Albrektsson, T ;

Johansson, C .

EUROPEAN SPINE JOURNAL, 2001, 10 (Suppl 2) :S96-S101

[4]

ALBREKTSSON T, 2003, IMPLANT CONCEPTS HIS, P809

[5] A predictive mechano-biological model of the bone-implant healing [J].

Ambard, Dominique ;

Swider, Pascal .

EUROPEAN JOURNAL OF MECHANICS A-SOLIDS, 2006, 25 (06) :927-937

[6] Modelling the early phases of bone regeneration around an endosseous oral implant [J].

Amor, N. ;

Geris, L. ;

Vander Sloten, J. ;

Van Oosterwyck, H. .

COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING, 2009, 12 (04) :459-468

[7] Measurement of shear elasticity and viscosity of rubberlike materials [J].

Andreev, V. G. ;

Burlakova, T. A. .

ACOUSTICAL PHYSICS, 2007, 53 (01) :44-47

[8]

[Anonymous], 2000, METHODS

[9] Osteoblast adhesion on biomaterials [J].

Anselme, K .

BIOMATERIALS, 2000, 21 (07) :667-681

[10] Electron microscopy, micro-analysis, and x-ray diffraction characterization of the mineral-like tissue deposited by human cementum tumor-derived cells [J].

Arzate, H ;

Alvarez-Pérez, MA ;

Alvarez-Fregoso, O ;

Wusterhaus-Chávez, A ;

Reyes-Gasga, J ;

Ximénez-Fyvie, LA .

JOURNAL OF DENTAL RESEARCH, 2000, 79 (01) :28-34

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