Chronic Constipation

被引：12

作者：

Brenner, Darren M. ^{[1
]}

Shah, Marmy ^{[2
]}

机构：

[1] Northwestern Univ, Feinberg Sch Med, Div Gastroenterol, 675 North St Clair Ave,Suite 17-250, Chicago, IL 60611 USA

[2] Loyola Univ, Med Ctr, Div Gastroenterol & Nutr, 2160 South First Ave,Bldg 54-Room 167, Maywood, IL 60153 USA

来源：

GASTROENTEROLOGY CLINICS OF NORTH AMERICA | 2016年 / 45卷 / 02期

关键词：

Constipation; Pathophysiology; Motility; Diagnostic testing; Anorectal manometry; Laxatives; Secretagogues; PLACEBO-CONTROLLED TRIAL; IDIOPATHIC CONSTIPATION; POLYETHYLENE-GLYCOL; CLINICAL UTILITY; COLONIC MOTILITY; ADULTS; ERYTHROMYCIN; MANAGEMENT; LUBIPROSTONE; MULTICENTER;

D O I：

10.1016/j.gtc.2016.02.013

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Chronic constipation is a common disorder that affects approximately 20% of the population and significantly impacts an individual's quality of life. The diagnosis can be made using standard criteria, and in the absence of alarm signs or symptoms, a determination of the underlying etiology/etiologies should be undertaken. In many instances, these will be gleaned from the history and physical examination. Specialized diagnostic testing may be warranted after the failure of initial laxative trials. Many therapeutic classes of laxatives exist with recent analyses indicating that practicing physicians prefer to use over-the-counter therapies in lieu of more strongly evidence-based prescription pharmaceuticals.

引用

页码：205 / +

页数：13

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